Survey of molecular mechanisms for avoiding rejection focusing on the genetic background of liver allograft

以同种异体肝遗传背景为中心的避免排斥反应的分子机制研究

• 批准号: 18K06786
• 负责人: Tajima Soichiro
• 金额: $ 2.83万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2018
• 资助国家: 日本
• 起止时间: 2018-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-18K06786/
• 关键词: 生体肝移植; 拒絶反応; 免疫抑制薬; 個別化医療; 免疫寛容; IFN-γ; タクロリムス; 肝移植

项目成果

Neutrophil Gelatinase-Associated Lipocalin Is Not Associated with Tacrolimus-Induced Acute Kidney Injury in Liver Transplant Patients Who Received Mycophenolate Mofetil with Delayed Introduction of Tacrolimus

• DOI: 10.3390/ijms20123103
• 发表时间: 2019-06
• 期刊: International Journal of Molecular Sciences
• 影响因子: 5.6
• 作者: Mio Fukuda;K. Suetsugu;Soichiro Tajima;Yurie Katsube;Hiroyuki Watanabe;N. Harada;T. Yoshizumi;N. Egashira;M. Mori;S. Masuda

Biomarkers for individualized dosage adjustments in immunosuppressive therapy using calcineurin inhibitors after organ transplantation

• DOI: 10.1038/s41401-018-0070-2
• 发表时间: 2019-02-01
• 期刊: ACTA PHARMACOLOGICA SINICA
• 影响因子: 8.2
• 作者: Fu, Rao;Tajima, Soichiro;Masuda, Satohiro
• 通讯作者: Masuda, Satohiro

Development and Validation of A Liquid Chromatography-Tandem Mass Spectrometry Method to Simultaneously Measure Tacrolimus and Everolimus Concentrations in Kidney Allograft Biopsies After Kidney Transplantation

液相色谱-串联质谱法的开发和验证，可同时测量肾移植后同种异体移植肾活检中他克莫司和依维莫司的浓度

• DOI: 10.1097/ftd.0000000000000912
• 发表时间: 2022
• 期刊: Therapeutic Drug Monitoring
• 影响因子: 2.5
• 作者: Zhang Mengyu;Tajima Soichiro;Shigematsu Tomohiro;Noguchi Hiroshi;Kaku Keizo;Tsuchimoto Akihiro;Okabe Yasuhiro;Egashira Nobuaki;Ieiri Ichiro
• 通讯作者: Ieiri Ichiro

Urinary Microtubule-Associated Protein 1 Light Chain 3 and Neutrophil Gelatinase-Associated Lipocalin, as Potential Noninvasive Biomarkers for Subclinical Rejection at 3 Months after kidney Transplantation

尿微管相关蛋白 1 轻链 3 和中性粒细胞明胶酶相关脂质运载蛋白，作为肾移植后 3 个月亚临床排斥的潜在非侵入性生物标志物

• 发表时间: 2019
• 作者: Soichiro Tajima;Rao Fu;Mio Fukuda;Kimitaka Suetsugu;Yasuhiro Okabe;Satohiro Masuda
• 通讯作者: Satohiro Masuda

Relationship between autophagy and acute rejection after kidney transplant

自噬与肾移植术后急性排斥反应的关系

• 发表时间: 2018
• 作者: 2.Rao Fu;Soichiro Tajima;Kimitaka Suetsugu;Nanae Yamamoto;Yasuhiro Okabe;Satohiro Masuda
• 通讯作者: Satohiro Masuda