Multimodal analysis of chromatin 3D structure using deep learning in gynecological malignancies

使用深度学习对妇科恶性肿瘤染色质 3D 结构进行多模态分析

• 批准号: 20H03820
• 负责人: Sone Kenbun
• 金额: $ 11.32万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20H03820/
• 关键词: エピゲノム; ヒストン修飾; 子宮体癌; 卵巣癌; SUV39H2; PARP阻害剤; 子宮肉腫; ChIP-seq; ATAC-seq; 卵巣類内膜癌; 深層学習; 薬剤耐性; クロマチン立体構造; Hi-C解析; ChIP-seq法

项目成果

History of whole pelvis plus para-aortic radiation is a risk factor associated with febrile neutropenia during chemotherapy for recurrent cervical cancer

全骨盆加主动脉旁放疗史是复发性宫颈癌化疗期间出现发热性中性粒细胞减少症的危险因素

• DOI: 10.1007/s10147-021-01950-8
• 发表时间: 2021
• 影响因子: 3.3
• 作者: Nara Katsuhiko;Taguchi Ayumi;Tojima Yuri;Miyamoto Yuichiro;Tanikawa Michihiro;Sone Kenbun;Mori Mayuyo;Tsuruga Tetsushi;Yamamoto Takehito;Takenaka Ryosuke;Takada Tappei;Osuga Yutaka;Suzuki Hiroshi
• 通讯作者: Suzuki Hiroshi

Effect of murine double‐minute 2 inhibitors in preclinical models of advanced clear cell carcinomas originating from ovaries and kidneys

鼠双分钟 2 抑制剂对源自卵巢和肾脏的晚期透明细胞癌临床前模型的影响

• DOI: 10.1111/cas.14583
• 发表时间: 2020
• 影响因子: 5.7
• 作者: Kawata Yoshiko;Nagasaka Kazunori;Oda Katsutoshi;Makii Chinami;Takeuchi Makoto;Oki Shinya;Honjo Harunori;Kojima Machiko;Miyagawa Yuko;Taguchi Ayumi;Tanikawa Michihiro;Sone Kenbun;Hiraike Haruko;Matsumoto Yoko;Wada‐Hiraike Osamu;Ayabe Takuya;Osuga Yutaka;Fu
• 通讯作者: Fu

Usefulness of biopsy by office hysteroscopy for endometrial cancer: A case report

办公室宫腔镜活检对子宫内膜癌的有用性：病例报告

• DOI: 10.3892/mco.2020.2053
• 发表时间: 2020
• 影响因子: 1.2
• 作者: Sone Kenbun;Eguchi Satoko;Asada Kayo;Inoue Futaba;Miyamoto Yuichiro;Tanikawa Michihiro;Tsuruga Tetsushi;Mori?Uchino Mayuyo;Matsumoto Yoko;Hiraike?Wada Osamu;Oda Katsutoshi;Osuga Yutaka;Fujii Tomoyuki
• 通讯作者: Fujii Tomoyuki

MED1, a novel binding partner of BRCA1, regulates homologous recombination and R-loop processing

MED1 是 BRCA1 的新型结合伴侣，调节同源重组和 R 环加工

• DOI: 10.1038/s41598-022-21495-8
• 发表时间: 2022
• 影响因子: 4.6
• 作者: Honjoh Harunori;Tanikawa Michihiro;Wada;Oda Katsutoshi;Inaba Hirofumi;Kukita Asako;Kawata Yoshiko;Kusakabe Misako;Tsuchimochi Saki;Taguchi Ayumi;Miyamoto Yuichiro;Sone Kenbun;Tsuruga Tetsushi;Mori;Matsumoto Yoko;Osuga Yutaka
• 通讯作者: Osuga Yutaka

Transiently elevated D‐dimer levels post‐concentrated ascites reinfusion therapy cannot be used to predict deep vein thrombosis‐pulmonary embolism

浓缩腹水回输治疗后短暂升高的 D-二聚体水平不能用于预测深静脉血栓形成-肺栓塞

• DOI: 10.1111/jog.15162
• 发表时间: 2022
• 影响因子: 1.6
• 作者: Sone Kenbun;Taguchi Ayumi;Kawata Akira;Eguchi Satoko;Miyamoto Yuichiro;Tanikawa Michihiro;Uchino‐Mori Mayuyo;Iriyama Takayuki;Tsuruga Tetsushi;Osuga Yutaka
• 通讯作者: Osuga Yutaka