Analysis of the basics and modelling of the Flow-Field-Thermal-Gradient-Gas-Chromatography

流场热梯度气相色谱基础知识和建模分析

基本信息

批准号：
290980359
负责人：
Privatdozent Dr. Peter Boeker
金额：
--
依托单位：
Institut für Landtechnik (ILT)
依托单位国家：
德国
项目类别：
Research Grants
财政年份：
2016
资助国家：
德国
起止时间：
2015-12-31 至 2019-12-31
项目状态：
已结题

来源：
https://gepris.dfg.de/gepris/projekt/290980359?language=en
关键词：
Analysis basics modelling Flow Field

项目摘要

The aim of the research proposal is the analysis of the basics of a new gas chromatographic (GC) method with a longitudinal negative temperature gradient. With such a gradient the chromatographic bands are permanently focussed because the peak fronts are decelerated and the peak tails are accelerated, respectively. This focussing effect compensates the diffusive band broadening. As the temperature level of the column is enhanced simultaneously the substances on the column are trapped at a distinct temperature that is determined by the equivalence of the chromatographic velocity and the velocity of the temperature along the column. In the gradient field the substances therefore move along the column with a constant temperature without the increase in the classical GC mode. In the context of the previous research program of the applicant and following studies of trace gas analytics a technically simple realisation of the thermal gradient GC has been developed. For the first time it is now possible to study the basics of the thermal gradient gas chromatography (TG-GC) with this experimental setup. The first measurement results are quite promising. With measurement times below 60 s high chromatographic resolutions have been obtained. In contrast to the classical GC up to now only limited experiences and no systematic evaluations of the TG-GC are available. The concept promises a largely improved fast separation which is favourable for e.g. gas sensor systems, ion mobility spectrometry and in combination with mass spectrometry. Due to the reduced separation temperatures also thermally labile components such as some aroma compounds, biological substrates and also energetic materials can be separated and analysed by TG-GC.

该研究计划的目的是分析具有纵向负温度梯度的新型气相色谱 (GC) 方法的基础知识。通过这样的梯度，色谱带永久聚焦，因为峰前端分别被减速，峰尾被加速。这种聚焦效应补偿了扩散带展宽。随着柱的温度水平同时提高，柱上的物质被捕获在不同的温度下，该温度由色谱速度和沿柱的温度速度的等效性确定。因此，在梯度场中，物质沿着色谱柱以恒定的温度移动，而不会增加经典 GC 模式的温度。在申请人之前的研究计划和痕量气体分析研究的背景下，已经开发了热梯度GC的技术上简单的实现。现在首次可以使用此实验装置来研究热梯度气相色谱 (TG-GC) 的基础知识。第一次测量结果非常有希望。测量时间低于 60 秒，即可获得高色谱分辨率。与经典 GC 相比，迄今为止只有有限的经验，并且没有对 TG-GC 进行系统的评估。该概念有望大大改善快速分离，这有利于例如气体传感器系统、离子迁移谱分析以及与质谱分析的结合。由于分离温度降低，热不稳定成分（例如一些芳香化合物、生物底物以及含能材料）也可以通过 TG-GC 进行分离和分析。