Direct detection of silver nano particles in biological and environmental samples

直接检测生物和环境样品中的银纳米颗粒

基本信息

批准号：
281446113
负责人：
Professorin Dr. Kerstin Leopold
金额：
--
依托单位：
Institut für Analytische und Bioanalytische Chemie
依托单位国家：
德国
项目类别：
Research Grants
财政年份：
2015
资助国家：
德国
起止时间：
2014-12-31 至 2018-12-31
项目状态：
已结题

来源：
https://gepris.dfg.de/gepris/projekt/281446113?language=en
关键词：
Direct detection silver nano particles

项目摘要

Nanotechnology is still an emerging area in research and industry and so far several hundreds of different consumer products include nanomaterials. About a fifth of all consumer products comprise silver nanoparticles. Silver nanoparticles are often added to cosmetics, hygiene, and health care products as well as in food and food contact materials. Their broad application requires a new assessment of silver, i.e. silver nanoparticle risk to human health and environment. However, official bodies are unable to give a definite opinion on basis of the currently available data. For this purpose more data has to be gained and large sample series are to be studied. In this context, there is an urgent need for reliable and robust analytical methods for nanoparticle detection, especially in complex sample matrices and large sample series. In addition, from December 2014 on, labelling of nanomaterials in food will be mandatory in the EU. Hence, controlling this obligation will require suitable analytical methods. Several approaches are currently objects of research and are discussed in detail in the state-of-the-art of the present proposal. In the planed project, a new method will be developed, allowing fast and cost-effective screening of large sample series for the presence of silver nanoparticles. In particular the developed method will be able to detect directly and selectively silver nanoparticles in solid complex matrices without elaborative sample preparation. This will be achieved by application of direct solid sampling high-resolution continuum source graphite furnace atomic absorption spectrometry. In preliminary experiments we could show that atomisation delay and atomisation rate are significant indicators for the presence of silver nanoparticles. In the planed project this approach will be further pursued in order to develop a new method for detection and distinction of silver nanoparticles and silver ions in relevant solid and complex liquid samples. The advantages of such an approach are obvious: The analytical process is shortened, because sample preparation is minimised to sample homogenisation. Extraction or separation of nanoparticles from the matrix is unnecessary. Hence, a higher samples throughput is achieved, no reagents are required and no chemical wastes for disposal occur. This makes the method economical and ecological beneficial (green analytical chemistry; sustainability). Moreover, no manipulation of the original samples occurs which minimises undesired transformation of the nanoparticles in the course of the analytical procedure.

纳米技术仍然是研究和行业的新兴领域，到目前为止，数百种不同的消费产品包括纳米材料。所有消费产品中约有五分之一包括银纳米颗粒。银纳米颗粒通常添加到化妆品，卫生和医疗保健产品以及食品和食品接触材料中。他们的广泛应用需要对白银进行新的评估，即对人类健康和环境的银纳米颗粒风险。但是，官方机构无法根据当前可用的数据发表明确的意见。为此，必须获得更多数据，并将研究大型样本系列。在这种情况下，迫切需要对纳米颗粒检测的可靠且可靠的分析方法，尤其是在复杂的样品矩阵和大型样品系列中。此外，从2014年12月开始，欧盟将必须将纳米材料的标签标签。因此，控制这项义务将需要合适的分析方法。目前，几种方法是研究对象，并在本提案的最新提案中进行了详细讨论。在计划的项目中，将开发一种新方法，从而可以快速且具有成本效益的大型样本系列，以在存在银纳米颗粒的情况下。特别是，开发的方法将能够直接和选择性地检测出无需详细样品制备的固体复合矩阵中的银纳米颗粒。这将通过应用直接固体采样高分辨率连续源石墨炉原子吸收光谱法实现。在初步实验中，我们可以证明雾化延迟和雾化速率是银纳米颗粒存在的重要指标。在计划的项目中，将进一步采用这种方法，以开发一种新方法，以检测和区分相关的固体和复杂液体样品中的银纳米颗粒和银离子。这种方法的优点是显而易见的：缩短了分析过程，因为样品制备被最小化以样本均质化。不需要从基质中提取或分离纳米颗粒。因此，实现了较高的样品吞吐量，不需要试剂，也没有发生化学废物以处置。这使得方法经济和生态有益（绿色的分析化学；可持续性）。此外，在分析程序过程中，没有任何原始样品的操纵最小化纳米颗粒的不想要的转换。

项目成果

期刊论文数量（6）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Analytical strategies to the determination of metal-containing nanoparticles in environmental waters

DOI：
10.1016/j.trac.2016.03.026
发表时间：
2016-11
期刊：
Trends in Analytical Chemistry
影响因子：
0
作者：
K. Leopold;A. Philippe;K. Wörle;G. Schaumann
通讯作者：
K. Leopold;A. Philippe;K. Wörle;G. Schaumann

Retention and remobilization mechanisms of environmentally aged silver nanoparticles in an artificial riverbank filtration system.

DOI：
10.1016/j.scitotenv.2018.07.079
发表时间：
2018-12
期刊：
The Science of the total environment
影响因子：
0
作者：
L. Degenkolb;G. Metreveli;A. Philippe;Anja Brandt;K. Leopold;Lisa Zehlike;H. Vogel;G. Schaumann;T. Baumann;M. Kaupenjohann;F. Lang;S. Kumahor;S. Klitzke
通讯作者：
L. Degenkolb;G. Metreveli;A. Philippe;Anja Brandt;K. Leopold;Lisa Zehlike;H. Vogel;G. Schaumann;T. Baumann;M. Kaupenjohann;F. Lang;S. Kumahor;S. Klitzke

Sizing gold nanoparticles using graphite furnace atomic absorption spectrometry