CAS-MNP: Understanding the Interactions Between Small Molecules and Plastic Nanoparticles for Environmental Remediation and Sensing Using Nuclear Magnetic Resonance

CAS-MNP：了解小分子和塑料纳米颗粒之间的相互作用，用于环境修复和核磁共振传感

• 批准号: 2304888
• 负责人: Leah Casabianca
• 金额: $ 50.56万
• 依托单位: Clemson University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2304888&HistoricalAwards=false
• 关键词: CAS; MNP; Understanding; Interactions; Between

With support from the Environmental Chemical Sciences program of the Division of Chemistry and the Established Program to Stimulate Competitive Research (EPSCoR), Leah Casabianca and her team at Clemson University will carry out experiments aimed at understanding the fundamental nature of binding between nanoscale plastic particles and small molecule pollutants. Plastic pollution is a growing environmental concern, made worse by the increasing use of plastic during the coronavirus pandemic. Large plastic particles break down in the environment to eventually form plastic nanoparticles. These particles may have a variety of surface characteristics due to the variable conditions experienced by the plastics in polluted waterways. Plastic nanoparticles also have a large surface-to-volume ratio and can be porous, allowing them to easily sorb small molecule contaminants that may also be present in polluted waterways. If plastic nanoparticles are ingested by wildlife or humans, these toxic small molecules may leach out of the plastic and cause harm. As part of the project, Dr. Casabianca’s team will participate in summer camps sponsored by Clemson’s Programs for Educational Enrichment and Retention (PEER) and Women in Science and Engineering (WISE) programs and will also develop demonstrations for high-school students that relate chemistry to the problem of nanoscale plastic pollution. The project will make use of Saturation-Transfer Difference Nuclear Magnetic Resonance (STD-NMR) spectroscopy to test different types of plastics (polyethylene, polypropylene, and polyvinyl chloride) for their ability to bind different contaminants. Competition STD-NMR will be used to investigate how other substances present in polluted waterways influence sorption of potential contaminants. Beyond just binding constants, the atomic site-specific nature of NMR spectroscopy and detailed structural information that it can provide will be used to understand the driving forces that are responsible for binding. Finally, in this project, the Clemson team will endeavor to develop new NMR methods to answer some the next questions on the horizon of environmental remediation and sensing.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在化学系环境化学科学项目和刺激竞争性研究既定项目 (EPSCoR) 的支持下，克莱姆森大学的 Leah Casabianca 和她的团队将开展实验，旨在了解纳米级塑料颗粒与塑料颗粒之间结合的基本性质。小分子污染物。塑料污染是一个日益严重的环境问题，在冠状病毒大流行期间，大塑料颗粒在环境中分解，最终形成塑料纳米颗粒，使情况变得更加严重。由于塑料在受污染水道中经历的变化条件而具有多种表面特性塑料纳米粒子还具有较大的表面积与体积比并且可以是多孔的，使它们能够轻松吸附也可能存在于受污染水道中的小分子污染物。如果塑料纳米颗粒被野生动物或人类摄入，这些有毒的小分子可能会从塑料中渗出并造成伤害。作为该项目的一部分，卡萨比安卡博士的团队将参加赞助的夏令营。由克莱姆森大学的教育丰富和保留计划 (PEER) 和科学与工程女性 (WISE) 计划负责，还将为高中生制作演示，将化学与纳米级塑料污染问题联系起来。该项目将利用饱和度。传递差核磁共振 (STD-NMR) 光谱法可测试不同类型的塑料（聚乙烯、聚丙烯和聚氯乙烯）与不同塑料的结合能力竞争 STD-NMR 将用于研究受污染水道中存在的其他物质如何影响潜在污染物的吸附，除了结合常数之外，NMR 光谱的原子位点特异性及其可提供的详细结构信息也将用于研究污染水道中存在的其他物质如何影响潜在污染物的吸附。最后，在这个项目中，克莱姆森团队将努力开发新的核磁共振方法，以回答环境修复和传感领域的一些后续问题。该奖项反映了这一点。通过使用基金会的智力价值和更广泛的影响审查标准进行评估，NSF 的法定使命被认为值得支持。