Conference: A workshop to understand the current needs for advancing living sentinel research

会议：了解当前推进活体哨点研究需求的研讨会

• 批准号: 2317614
• 负责人: Jonathan Silberg
• 金额: $ 7.61万
• 依托单位: William Marsh Rice University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2317614&HistoricalAwards=false
• 关键词: Conference; workshop; understand; current; needs

The current global pandemic and the risk of future outbreak events has provided a strong motivation to rethink how we monitor and respond to emergent threats. A potential solution is to create sentinel living systems that detect, recognize, actuate, and mitigate emergent biological threats. To create strong stakeholder engagement and define a vision for sentinel systems, a series of activities will be organized that lead to the development of a research roadmap. This roadmap will frame the foundational challenges in detecting and recognizing health and environmental threats in real time and building devices from living and non-living parts that mitigate those threats using synthetic biology. By bringing together researchers from diverse backgrounds and disciplines, including biology, engineering, and materials, this workshop will draw from broad perspectives and expertise ensuring a robust and rigorous discussion that supports the development of a roadmap that advances in the field. The goal of the proposed workshop is to bring together leading scholars in synthetic biology, materials science, and electrical engineering to discuss the foundational knowledge that is required to create smart technologies that detect, recognize, actuate, and mitigate emergent biological threats. Specifically, it will accomplish four objectives. First, prior to the workshop, diverse stakeholders will be engaged using a virtual mechanism to introduce the workshop goals and ask participants to share ideas in response to a set of defined questions. This information will be used to refine the agenda and materials for the workshop to ensure that it stimulates robust stakeholder discussions. Second, focused stakeholder engagement will be accomplished using an in-person workshop. This will involve defining a frame for discussions and a series of breakout sessions where smaller groups of participants discuss and provide feedback on specific topic points. Third, to broaden the in-person workshop participation, virtual breakout sessions will be used to allow remote participants to contribute in real time. These groups will contain stakeholders from different disciplines to bring together different perspectives. Finally, using the digital notes developed through the meeting, participants will be asked to develop a roadmap document in an article form that contains the outcome of recommendations, which will be disseminated to the broader community through a publication.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

当前的全球大流行和未来爆发事件的风险为我们如何监控和应对新兴威胁的方式提供了强大的动力。一个潜在的解决方案是创建前哨生活系统，以检测，识别，启动和减轻新兴的生物学威胁。为了建立强大的利益相关者参与并定义了哨兵系统的愿景，将组织一系列活动，以开发研究路线图。该路线图将构成实时检测和认识到健康和环境威胁的基本挑战，并从使用合成生物学来减轻这些威胁的生活和非生活部分建造设备。通过将来自不同背景和学科的研究人员汇集在一起​​，包括生物学，工程和材料，该研讨会将从广义的角度和专业知识中借鉴，以确保强大而严格的讨论，以支持该领域发展的路线图的发展。拟议的研讨会的目的是将合成生物学，材料科学和电气工程领域的领先学者汇集在一起​​，以讨论创建智能技术所需的基础知识，以检测，识别，鉴定，动摇和减轻新兴的生物学威胁。具体来说，它将实现四个目标。首先，在研讨会之前，不同的利益相关者将使用虚拟机制介绍研讨会目标，并要求参与者分享想法，以回答一系列定义的问题。该信息将用于完善研讨会的议程和材料，以确保刺激稳健的利益相关者讨论。其次，专注的利益相关者参与将使用面对面的研讨会来完成。这将涉及定义讨论的框架和一系列突破性会议，较小的参与者群体讨论并提供有关特定主题点的反馈。第三，为了扩大面对面的研讨会的参与，将使用虚拟突破性会议来实时实时贡献。这些群体将包含来自不同学科的利益相关者，以汇集不同的观点。最后，使用通过会议开发的数字说明，将要求参与者以文章形式开发路线图文件，其中包含建议的结果，该文件将通过出版物通过出版物将其传播给更广泛的社区。该奖项反映了NSF的法定任务，并通过使用该基金会的智力功能和广泛的影响来评估NSF的法定任务。