REU Site: Enabling Technologies and New REU Approaches to Engineer Complex Tissues

REU 网站：工程复杂组织的支持技术和 REU 新方法

• 批准号: 2243993
• 负责人: Anthony Atala
• 金额: $ 38.74万
• 依托单位: Wake Forest University School of Medicine
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-10-01 至 2026-09-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2243993&HistoricalAwards=false
• 关键词: REU; Site; Enabling; Technologies; New

This three-year renewal REU Site, Enabling Technologies and New REU Approaches to Engineer Complex Tissues, will engage diverse cohorts of 10 undergraduate students each summer in highly collaborative, team-based 10-week multidisciplinary research projects in regenerative medicine at the Wake Forest Institute for Regenerative Medicine (WFIRM). A challenge facing the regenerative medicine field and the broader STEM disciplines is developing the next generation of skilled bioengineers. Regenerative medicine is a multidisciplinary field involving engineering and other STEM disciplines. Students will focus on learning about enabling technologies and biomanufacturing approaches in regenerative medicine and the emerging field of biofabrication. The REU experience is supplemented with additional program activities and education on the research process, hands-on instrumentation, workshops on bioethics, responsible conduct of research, effective oral and written communication, professional development, networking, and career opportunities topics. WFIRM has been at the forefront in RM research for nearly two decades and is an internationally recognized center of excellence in research and training.This renewal REU Site, Enabling Technologies and New REU Approaches to Engineer Complex Tissues, will engage diverse cohorts of 10 undergraduate students each summer for three years in highly collaborative, team-based 10-week multidisciplinary research projects in regenerative medicine (RM) at the Wake Forest Institute for Regenerative Medicine (WFIRM). Students will learn about enabling technologies and biomanufacturing approaches and the emerging field of biofabrication. This REU, emphasizing RM enabling technologies and biomanufacturing, is focused on two convergent research areas: 1) enabling technologies biomanufacturing and biofabrication (3D bioprinting, bioreactors, encapsulation and bioengineering of multi-cellular tissue constructs (organoids/body-on-a-chip) as modeling platforms and 2) stem cells/gene editing as applied to engineering one or more tissue/organ application. The REU experience is supplemented with additional program elements and education on the research process, hands-on instrumentation, workshops on bioethics, responsible conduct of research, effective oral and written communication, professional development, networking, and career opportunities topics. Also included is an introductory course to familiarize students with the essentials of the regenerative medicine field and seminars on “hot” topics in the field. All students will present their research findings throughout the summer and at a final research day symposium. WFIRM has been at the forefront in RM research for nearly two decades and is an internationally recognized center of excellence in research and training.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个为期三年的更新 REU 站点，即工程复杂组织的支持技术和新 REU 方法，每年夏天将吸引 10 名本科生组成的不同群体，在维克森林研究所进行高度协作、基于团队的为期 10 周的再生医学多学科研究项目再生医学领域和更广泛的 STEM 学科面临的挑战是培养下一代熟练的生物工程师。再生医学是一个多学科领域工程和其他 STEM 学科。学生将重点学习再生医学和新兴生物制造领域的支持技术和生物制造方法。REU 的经验将通过额外的项目活动和研究过程教育、实践仪器、生物伦理学研讨会、负责任的研究进行补充。 、有效的口头和书面沟通、专业发展、网络和职业机会等主题近二十年来 WFIRM 一直处于 RM 研究的前沿，是国际公认的研究和培训卓越中心。此次更新的 REU 网站，使能。 REU 工程复杂组织的技术和新方法将每年夏天吸引 10 名本科生组成的不同群体，为期三年，在维克森林再生医学研究所开展高度协作、基于团队的为期 10 周的再生医学 (RM) 多学科研究项目（WFIRM）。学生将了解使能技术和生物制造方法以及生物制造的新兴领域，该 REU 强调 RM 使能技术和生物制造，重点关注两项融合研究。领域：1) 生物制造和生物制造使能技术（3D 生物打印、生物反应器、多细胞组织构建体（类器官/芯片上的身体）的封装和生物工程作为建模平台，2) 应用于工程的干细胞/基因编辑REU 的一项或多项组织/器官应用经验还辅以额外的项目要素和研究过程教育、仪器操作、生物伦理学研讨会、负责任的研究行为、有效的口头指导。还包括书面交流、专业发展、网络和职业机会主题，让学生熟悉再生医学领域的基本知识，并举办有关该领域“热门”主题的研讨会。近二十年来，WFIRM 一直处于 RM 研究的前沿，是国际公认的研究和培训卓越中心。该奖项是 NSF 的法定使命，并被认为值得通过以下方式获得支持：评估使用基金会的智力价值和更广泛的影响审查标准。