FMSG:ECO: CAS:From Carbon Dioxide to Future Bioplastic Manufacturing for Environmental Sustainability

FMSG：ECO：CAS：从二氧化碳到未来生物塑料制造以实现环境可持续性

• 批准号: 2229160
• 负责人: Susie Dai
• 金额: $ 50万
• 依托单位: Texas A&M AgriLife Research
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2229160&HistoricalAwards=false
• 关键词: FMSG; ECO; CAS; Carbon; Dioxide

Replacing petroleum-based products with inexpensive, renewable, natural materials is essential for sustainable development and will significantly impact the polymer industry and the environment. Petroleum-based plastic materials have exceeded most other man-made materials and are present as must-have materials in modern life. It is estimated that the total amount of plastic resins and fibers manufactured from 1950 through 2015 is 7800 million tons, half of which was produced in the past decades. Biodegradable plastics have been long sought-after as alternatives to petrochemical plastics to promote environmental sustainability. Even though bioplastics provide substantive environmental benefits, the current manufacturing cost is relatively high. In this Future Manufacturing Seed Grant (FMSG) project, the project team will develop a new manufacturing process to convert CO2 to bioplastics (polyhydroxyalkanoates, PHA) and design bioplastics composite to enable future manufacturing. CO2 will be converted to edible microbial nutrients via a process known as electrocatalysis, and the nutrients will further be used by bacteria to produce PHA. Microbe-derived PHA will be used to make bioplastic composites. The project will engage undergraduate and graduate students, utilize a university training center to educate broad audiences, and build global impacts in Africa.The project aims to develop a new manufacturing process to convert CO2 to bioplastics (polyhydroxyalkanoates, PHA) and design bioplastics composite for broader applications. Traditional industrial fermentation has an inherent carbon efficiency limitation using sugar-based feedstock. The limited reducing equivalent supply during carbon conversion inevitably leads to carbon emission and lowers carbon efficiency in heterotrophic microorganisms. The proposed research will create a cost-effective manufacturing of industrial quality bioplastics. The research will establish an electrochemistry-bioconversion hybrid system for efficient and cost-effective PHA production. Electrolysis-supported catalytic pathways for CO2 conversion to acetate, ethanol, and propionate will be created and optimized. The team will integrate a two-step tandem process with a state-of-the-art Cu catalyst to achieve a highly selective acetate/ethanol production at high reaction rates. Pseudomonas strains will be engineered to convert C2 and C3 intermediates to PHA with a high efficiency. Techno-economic analysis (TEA) and life cycle analysis (LCA) will be measured to evaluate the economic and environmental impacts of new created PHA composites. The fundamental knowledge gained from this process will bring transformative changes to the current manufacturing and climate mitigation.This project is jointly funded by the Division of Molecular and Cellular Biosciences in the Directorate for Biological Sciences, the Division of Chemical, Bioengineering, Environmental, and Transport Systems in the Directorate for Engineering, and the Division of Chemistry in the Directorate of Mathematical and Physical Sciences.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

用廉价、可再生的天然材料取代石油产品对于可持续发展至关重要，并将对聚合物行业和环境产生重大影响。石油基塑料材料已超过大多数其他人造材料，成为现代生活的必备材料。据估计，1950年至2015年生产的塑料树脂和纤维总量为78亿吨，其中一半是过去几十年生产的。可生物降解塑料作为石化塑料的替代品一直受到追捧，以促进环境的可持续性。尽管生物塑料提供了实质性的环境效益，但目前的制造成本相对较高。在这个未来制造种子资助 (FMSG) 项目中，项目团队将开发一种新的制造工艺，将二氧化碳转化为生物塑料（聚羟基脂肪酸酯，PHA），并设计生物塑料复合材料以实现未来制造。 CO2 将通过电催化过程转化为可食用的微生物营养物质，而这些营养物质将进一步被细菌利用来生产 PHA。微生物衍生的 PHA 将用于制造生物塑料复合材料。该项目将吸引本科生和研究生，利用大学培训中心教育广大受众，并在非洲产生全球影响。该项目旨在开发一种新的制造工艺，将二氧化碳转化为生物塑料（聚羟基脂肪酸酯，PHA），并设计生物塑料复合材料更广泛的应用。使用糖基原料的传统工业发酵具有固有的碳效率限制。碳转化过程中有限的还原当量供应不可避免地导致异养微生物的碳排放并降低碳效率。拟议的研究将创造一种具有成本效益的工业品质生物塑料制造方法。该研究将建立一个电化学-生物转化混合系统，用于高效且经济高效的 PHA 生产。将创建和优化电解支持的二氧化碳转化为乙酸盐、乙醇和丙酸盐的催化途径。该团队将两步串联工艺与最先进的铜催化剂相结合，以高反应速率实现高选择性的乙酸盐/乙醇生产。假单胞菌菌株将被设计为高效地将 C2 和 C3 中间体转化为 PHA。将测量技术经济分析 (TEA) 和生命周期分析 (LCA)，以评估新型 PHA 复合材料的经济和环境影响。从这个过程中获得的基础知识将为当前的制造业和气候缓解带来革命性的变化。该项目由生物科学局分子和细胞生物科学部、化学、生物工程、环境和运输部共同资助该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查进行评估，被认为值得支持 标准。