Collaborative Research: A Phylogenomic Study of a Hyper-Diverse Flowering Plant Lineage, Subfamily Lamioideae (Lamiaceae)

合作研究：唇形科亚科超多样化开花植物谱系的系统基因组研究

• 批准号: 2139311
• 负责人: Charlotte Lindqvist
• 金额: $ 46.81万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2139311&HistoricalAwards=false
• 关键词: Collaborative; Research; Phylogenomic; Study; Hyper; Collaborative; Research; Phylogenomic; Study; Hyper

Understanding the evolutionary processes that lead to speciation remains a fundamental challenge in biology. As the sixth largest flowering plant family, the mint family (Lamiaceae) is exceptionally important ecologically, ethnobotanically, and floristically. Within the mint family, the second largest subfamily, the lamioid mints (Lamioideae), serves as an excellent model for exploring global patterns of plant diversification and evolutionary radiation, or a rapid increase in the number of species in a clade. This research will use high throughput DNA sequencing technologies to build a robust understanding of evolutionary relationships in the lamioid mints. The findings from this project will be of broad value to systematists, evolutionary biologists, and ecologists by helping close gaps in our fundamental understanding of how plants diversify, including the evolution of early flowering plants and colonization of newly formed habitats, such as volcanic islands. Information gathered from this project will also improve our knowledge of the comparative biology of lamioid mints, guide new product discovery, and aid in the development of conservation measures for endangered species. This project incorporates extensive opportunities for education and career training at multiple levels, including high school teachers, undergraduate students, a postdoctoral researcher, and an early-career female faculty. The project team will offer public seminars about lamioid mints, highlighting their research findings and broader implications. An important component of this project is to train and mentor undergraduate students, and twelve undergraduate students from Missouri Western State University will become actively involved in various aspects of this project.The lamioid mints, which have been categorized into 13 tribes, have a near cosmopolitan distribution, with most taxa found in the Old World and only two lineages having colonized the New World and Hawaiian Islands. Despite this widespread distribution and diversity, a solid phylogenomic framework of the lamioid mints, from which patterns of diversification and links to shifts in distribution, ecology, and genome dynamics can be explored, is still lacking. This project will utilize next-generation sequencing approaches involving targeted enrichment, transcriptomics, and broad taxonomic sampling from field and herbaria across the US to build a robust phylogenetic platform of the lamioid mints. The following major goals will be accomplished: 1) Circumscribe the major clades of Lamioideae and their interrelationships and make necessary taxonomic changes, including determining the placement of the two tribes comprising New World members, Stachydeae and Synandreae, and the basal tribes, Gomphostemmateae and Pogostemoneae; 2) Estimate the timing of key evolutionary events and rates of diversification; 3) Link diversifications in Lamioideae, particularly within Stachydeae and Synandreae, with shifts in biogeography, whole genome and gene duplication, and character trait evolution to identify possible key innovations and apparent repeated evolution of morphological characters.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

了解导致物种形成的进化过程仍然是生物学的基本挑战。作为第六大开花植物家族，薄荷科（Lamiaceae）在生态，民族植物和花店上非常重要。在薄荷家族中，第二大亚科，Lamioid Mints（Lamioideae）是探索植物多样化和进化辐射的全球模式的绝佳模型，或者在进化枝中的物种数量迅速增加。这项研究将使用高吞吐量DNA测序技术来建立对Lamioid MINT中进化关系的强有力理解。该项目的发现将对系统主义者，进化生物学家和生态学家具有广泛的价值，这是通过帮助我们对植物如何多样化的基本理解的差距，包括早期开花植物的发展以及新形成的栖息地的殖民化，例如火山岛。从该项目中收集的信息还将提高我们对Lamioid Mints比较生物学的了解，引导新产品发现，并帮助制定濒危物种的保护措施。该项目融合了多个级别的教育和职业培训的大量机会，包括高中教师，本科生，博士后研究员和早期职业女教师。项目团队将向公开研讨会提供有关Lamioid Mints的研讨会，强调他们的研究结果和更广泛的影响。该项目的一个重要组成部分是培训和导师的本科生，来自密苏里西部州立大学的十二名本科生将积极参与该项目的各个方面。将13个部落分类为13个部落，已在旧世界中发现了大多数分类，在旧世界中发现了大多数分类，并且只有两个领域，并且只有两个领域，并且只有两个新世界和新世界是霍伊岛，并将其化为新世界。尽管存在这种广泛的分布和多样性，但仍缺乏多样化的固定系统基因组框架，从中可以探索分布，生态学和基因组动力学的多样化模式以及与分布的变化的链接。该项目将利用涉及来自美国田间和草药的广泛分类学采样的下一代测序方法，以构建Lamioid Mints的强大系统发育平台。将实现以下主要目标：1）限制Lamioideae及其相互关系的主要进化片，并进行必要的分类学更改，包括确定由新世界成员组成的两个部落的位置，包括新世界成员，Stachydeae和synandreae，以及基底部落，基底部落，gomphostemmatemmateae and pogostemostemeaeeae; 2）估计关键进化事件的时机和多样化的速度； 3）与生物地理学，整个基因组和基因重复以及特征性状进化的转变，以确定可能的关键创新和形式的反复演变，这反映了NSF的法定任务和宽广的依据，该链接依次是通过评估，这反映了Intectial and Intelliatial，将依据的依据与宽广的影响相关联。