SBIR Phase I: Development of a nasal compression device with medicated intranasal sponges for the treatment of nosebleeds in any setting

SBIR 第一阶段：开发带有含药鼻内海绵的鼻压缩装置，用于治疗任何情况下的流鼻血

• 批准号: 2136297
• 负责人: Elizabeth Clayborne
• 金额: $ 25.6万
• 依托单位: NASACLIP, INC.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-03-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2136297&HistoricalAwards=false
• 关键词: SBIR; Phase; Development; nasal; compression

This Small Business Innovation Research (SBIR) Phase I project is to help treat the common nosebleed. Nosebleeds are a common problem that 60% of people experience. The proposed project develops an effective and low-cost innovative technology to address this by combining external pressure with intranasal medication when placed in a nominal manner by any user. The solution would provide a simple method that reduces the need for patients to visit health care services, and reduces the burden of health care providers for treating nosebleeds. The goal of this project is to design and develop an effective nosebleed treatment device for children and adults that combines external pressure using a prototype nasal clip with intranasal medication sponges. The objectives of this project include completing systematic studies towards (1) design and development of a nasal clip with pre-medicated intranasal sponges capable of consistently applying the proper amount of pressure and eluting the proper amount of medication when placed in a nominal manner, (2) testing of the device using a nosebleed model, (3) identifying manufacturing processes to commercialize and scale the device in a cost effective manner. The outcome will be a functional and lab tested nosebleed treatment clip.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个小型企业创新研究 (SBIR) 第一阶段项目旨在帮助治疗常见的鼻血。流鼻血是60%的人都经历过的常见问题。拟议的项目开发了一种有效且低成本的创新技术，通过将外部压力与任何用户以名义方式放置的鼻内药物相结合来解决这个问题。该解决方案将提供一种简单的方法，减少患者访问医疗保健服务的需要，并减轻医疗保健提供者治疗鼻血的负担。该项目的目标是为儿童和成人设计和开发一种有效的鼻出血治疗装置，该装置将使用原型鼻夹和鼻内药物海绵的外部压力相结合。该项目的目标包括完成系统研究，以实现 (1) 设计和开发带有预加药鼻内海绵的鼻夹，当以名义方式放置时，能够持续施加适当的压力并洗脱适量的药物，（ 2) 使用鼻血模型测试设备，(3) 确定制造工艺，以经济高效的方式将设备商业化和规模化。结果将是一个经过功能性和实验室测试的鼻血治疗夹。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。