IRES Track I: A U.S.-Ireland Partnership for an International Graduate Research Experience in Biopharmaceutical Processing

IRES 第一轨：美国-爱尔兰合作伙伴关系，提供生物制药加工方面的国际研究生研究经验

• 批准号: 2107401
• 负责人: Geoffrey Toner
• 金额: $ 30万
• 依托单位: Thomas Jefferson University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-12-01 至 2024-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2107401&HistoricalAwards=false
• 关键词: IRES; Track; U.S.; Ireland; Partnership

The U.S. economy is faced with unprecedented challenges in numerous industry sectors. These challenges underscore a compelling opportunity to prepare the next generation of biopharmaceutical scientists who are specially trained in a field that our world desperately needs. Despite the fact that international partnerships between U.S. and non-U.S.-based sites are often challenging to arrange, especially in the area of biomanufacturing, we have a unique opportunity to execute a Track 1 International Research Experience (IRES) that capitalizes on our existing collaboration between Thomas Jefferson University and Ireland’s National Institute for Bioprocessing Research and Training (NIBRT), a non-academic research enterprise. The program will provide a unique training and educational research experience in a world class facility, engage underrepresented minorities, and provide assistance to transition the participants to industry or advanced degree programs.Thomas Jefferson University proposes to engage its international training partner, the National Institute for Bioprocessing Research and Training (NIBRT) to enable global research in methodologies of bioanalytics and biomonitoring with the following goals: (1) Offer a specially selected cohort of students (N=6 each year) the opportunity to develop agile, analytical skills in biopharmaceutical process engineering with a prominent global leader so that they emerge as distinctively prepared. (2) Increase the inclusion of underrepresented minorities (URMs) in the life sciences and engineering through participation in biopharmaceutical process engineering and recruitment efforts. (3) Train and transition exceptionally prepared, highly competitive students into industry positions or advanced degree programs. Our long-term goals are to increase the workforce pipeline for the biopharmaceutical and vaccine industries, and foster U.S. manufacturing competitiveness in an area critically important to human health and national security. The biopharmaceutical industry is highly regulated and research and training opportunities at relevant sites are both difficult and costly. The meaningful relationship already in place between Philadelphia/Jefferson and NIBRT offers a powerful convergence of two thought leaders in establishing a novel and potentially transformative research training experience that capitalizes on our international exchange, existing curriculum, and world-class researchers and capabilities unmatched anywhere else on the globe. Furthermore, continued targeted efforts to engage URMs are critical to the evolution of the U.S.’s STEM workforce as the diversity of U.S. populations increase and we attempt to remain competitive in STEM fields. Finally, we intend to build this nascent international opportunity into a sustainable and long-term exchange in which U.S. and NIBRT trainees have global opportunities on either continent. In return, by securing this type of training and experiential learning, we will contribute significantly to a workforce that is desperately needed in the biomanufacturing industry and our findings will bolster the existing literature on the advantages of international STEM student training opportunities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

美国经济在众多行业领域面临着前所未有的挑战，这些挑战凸显了培养下一代生物制药科学家的绝佳机会，他们在我们的世界迫切需要的领域接受过专门培训。 -美国的地点通常很难安排，特别是在生物制造领域，我们有一个独特的机会来执行第一轨道国际研究经验（IRES），利用我们与托马斯杰斐逊大学和美国大学之间的现有合作爱尔兰国家生物加工研究和培训研究所 (NIBRT) 是一家非学术研究企业，该计划将在世界一流的设施中提供独特的培训和教育研究经验，吸引代表性不足的少数群体，并为参与者过渡到行业或行业提供帮助。托马斯杰斐逊大学提议与其国际培训合作伙伴国家生物加工研究和培训研究所 (NIBRT) 合作，以实现生物分析和生物监测方法学的全球研究，目标如下：(1)为专门挑选的学生群体（每年 6 名）提供机会，与全球杰出领导者一起培养生物制药工艺工程方面的敏捷分析技能，使他们做好充分准备 (2) 增加代表性不足的少数群体 (URM) 的包容性。 ）通过参与生物制药工艺工程和招聘工作，培训和过渡准备充分、竞争激烈的学生进入行业职位或高级学位课程。生物制药和疫苗行业，并在对人类健康和国家安全至关重要的领域培养美国制造业的竞争力。生物制药行业受到严格监管，相关地点的研究和培训机会既困难又昂贵。 /Jefferson 和 NIBRT 提供了两位思想领袖的强大融合，建立了一种新颖且具有潜在变革性的研究培训体验，该体验利用了我们的国际交流、现有课程以及世界一流的研究人员和其他任何地方都无法比拟的能力。此外，随着美国人口多样性的增加以及我们试图在 STEM 领域保持竞争力，持续有针对性地吸引 URM 对美国 STEM 劳动力的发展至关重要。最后，我们打算创造这一新兴的国际机会。进行可持续和长期的交流，使美国和 NIBRT 学员在任一大陆都拥有全球机会。作为回报，通过确保此类培训和体验式学习，我们将为该地区急需的劳动力做出重大贡献。生物制造行业和我们的研究结果将支持关于国际 STEM 学生培训机会优势的现有文献。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。