CAREER: Unlocking the potential of natural polymers for efficient removal of emerging contaminants from drinking water.

职业：释放天然聚合物的潜力，有效去除饮用水中的新兴污染物。

• 批准号: 2047762
• 负责人: Maria Peresin
• 金额: $ 69.16万
• 依托单位: Auburn University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2026-03-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2047762&HistoricalAwards=false
• 关键词: CAREER; Unlocking; potential; natural; polymers

NON-TECHNICAL SUMMARYIn this project, Dr. Maria Soledad Peresin aims to unlock the potential of certain components of plant or animal biomass to design biomaterials by advancing the fundamental understanding of naturally occurring systems to address critical issues of societal concern, such as the removal of emerging contaminants from drinking water.Polymers are natural or man-made chemicals that are composed of building blocks of smaller repeating molecules, as one would picture individual Legos® within a larger structure. Natural polymers, such as cellulose (from wood, soybean hulls, cotton, etc.), chitosan (from the outer shell of shellfish) and alginates (from algae) are sustainable and renewable resources that are an essential component of a circular economy, aimed at minimizing waste. Combining properties of different natural polymers is a way to develop a new generation of products that may replace traditional, non-renewable fossil fuel-based materials.This project will focus on understanding, developing and using renewable, natural polymers to design efficient and sustainable adsorbents, which are highly porous structures for the removal of contaminants. Dr. Peresin proposes an extensive study of a variety of polymer systems to maximize their potential adsorption capacity for removing contaminants from water bodies in different environmental conditions. Adsorption capacity of the polymers’ assemblies and their performance will be assessed using three model emerging aquatic contaminants, tetracycline (an antibiotic), ibuprofen (an analgesic) and sulfamethoxazole (an antibiotic). Dr. Peresin will use this research program as a platform for education with an impactful contribution to improving science literacy in the State of Alabama while contributing to local, national and global efforts to provide a sustainable method for cleaning drinking water. Younger generations have an increased environmental concern and awareness of the need to decrease our impact on the planet. Through her research and mentorship, Dr. Peresin hopes to advance career opportunities within the forest industry for environmentally conscience students with the development of novel processes and new products that contribute to the sustainable use of resources and economic benefit of society. This project is jointly funded by the Biomaterials Program in the Division of Materials Research, and the Established Program to Stimulate Competitive Research (EPSCoR). TECHNICAL SUMMARYThe overarching goals of this CAREER plan are 1) to uncover the principles that underlie the structure-property relationship between naturally occurring polysaccharides (PS) interactions, surface properties and their assembly for the design of macroscale adsorbents, 2) to use this platform to educate students on interfacial phenomena involved in cleaning water using natural resources, and 3) to contribute to global efforts to provide clean drinking water to society. Natural polymers are renewable resources, essential for the circular economy. Combining their properties is critical for developing the new generation of functional materials on lieu of traditional fossil-based materials. However, several challenges remain in order to deploy these materials, such as cost, performance and scale. The long-term research goal of this CAREER is to advance the knowledge that will enable the rational design of PS structures based on natural polymers for effective removal of emerging contaminants from drinking water. This CAREER proposal will provide a fundamental framework for elucidating the fine interplay between the composition, surface functionality, and the supramolecular structure of natural polymers, specifically PS such as cellulose and chitin, and their effect on interfacial interactions with emerging contaminants. Polymers self-assembly and their interfacial behavior have been extensively studied, however, more work is needed for understanding the correlation between the surface properties of natural PS assembly and their impact on the interfacial adsorption phenomena. During this five year CAREER award, the following hypotheses will be addressed: 1) PS interactions can be controlled by changing environmental conditions and macromolecules intrinsic properties, 2) entropic and enthalpic contributions to binding energy of PS assemblies will affect their swelling and adsorption capacity, 3) interfacial interactions resulting from the macromolecule assembly will determine the surface energy and chemistry of the PS structures, with a direct impact on the total sorption capacity. The majority of the work will be performed on cellulose and chitin (and their derivatives) as they are ideal for this project due to their abundancy, robust chemical structural, surface area and versatile surface functionality. To test the hypothesis the PI will use a combinatory approach that involves PS assemblies and adsorption studies on 2D model surfaces. These findings then will be translated to a 3D hydrogel system, produced through a bottom-up self-assembly approach. Adsorption capacity and performance will be assessed using three model of emerging contaminants namely, tetracycline (an antibiotic), ibuprofen (an analgesic) and 2,4-dichlorophenoxyacetic acid (an herbicide). These hypotheses will be tested with the following specific objectives 1) elucidate the nature of the PS interactions during their self-assembly; 2) understand the role of composition and surface functionality on PS assemblies swelling and supramolecular structure, 3) examine different routes for self-assembly of PS in 3D structures and 4) unveil the effects of supramolecular structure, composition and surface on the overall adsorption capacity of the PS assemblies.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

非技术摘要在该项目中，Maria Soledad Peresin 博士旨在通过推进对自然发生系统的基本理解来释放植物或动物生物质的某些成分设计生物材料的潜力，以解决社会关注的关键问题，例如去除饮用水中新出现的污染物。聚合物是天然或人造化学品，由较小的重复分子组成，就像人们想象的那样，单个乐高积木包含在较大的结构中，例如天然聚合物。纤维素（来自木材、大豆皮、棉花等）、壳聚糖（来自贝类外壳）和藻酸盐（来自藻类）是可持续和可再生资源，是循环经济的重要组成部分，旨在最大限度地减少浪费。研究不同天然聚合物的特性是开发新一代产品的一种方法，这些产品可能会取代传统的、不可再生的化石燃料材料。该项目将重点了解、开发和使用可再生的天然聚合物，以设计高效和可持续的产品吸附剂是用于去除污染物的高度多孔结构，Peresin 博士建议对各种聚合物系统进行广泛的研究，以最大限度地提高其在不同环境条件下从水体中去除污染物的潜在吸附能力。其性能将使用三种新出现的水生污染物模型进行评估：四环素（一种抗生素）、布洛芬（一种镇痛剂）和磺胺甲恶唑（一种Peresin 博士将利用该研究项目作为教育平台，为提高阿拉巴马州的科学素养做出有影响力的贡献，同时为地方、国家和全球提供可持续的饮用水清洁方法做出贡献。通过她的研究和指导，人们越来越关注环境问题，并认识到需要减少我们对地球的影响，佩雷辛博士希望通过开发新颖的工艺和新产品，为有环保意识的学生增加林业的就业机会。有助于资源的可持续利用和经济效益该项目由材料研究部的生物材料计划和刺激竞争研究既定计划 (EPSCoR) 共同资助。 技术摘要 该职业计划的总体目标是 1) 揭示构成该结构的原则。 -天然存在的多糖（PS）相互作用、表面特性及其组装之间的特性关系，用于设计宏观吸附剂，2）使用该平台来教育学生研究利用自然资源净化水的界面现象，以及3）为全球为社会提供清洁饮用水做出贡献。天然聚合物是可再生资源，对于循环经济至关重要，结合其特性对于开发新一代聚合物至关重要。然而，部署这些材料仍然存在一些挑战，例如成本、性能和规模，这一职业的长期研究目标是推进能够实现合理化的知识。基于天然聚合物的PS结构设计该职业提案将为阐明天然聚合物（特别是纤维素和甲壳素等聚苯乙烯）的组成、表面功能和超分子结构之间的精细相互作用及其对水的影响提供一个基本框架。聚合物与新兴污染物的界面相互作用及其界面行为已被广泛研究，但是，需要做更多的工作来了解天然 PS 组装的表面特性及其对它们的影响之间的相关性。在这五年的职业奖中，将解决以下假设：1）PS 相互作用可以通过改变环境条件和大分子固有特性来控制，2）PS 组件的熵和焓贡献将影响其结合能。膨胀和吸附能力，3）大分子组装产生的界面相互作用将决定PS结构的表面能和化学性质，直接影响总吸附能力。纤维素和甲壳素（及其衍生物）因其丰富的化学结构、表面积和多功能的表面功能而成为该项目的理想选择。为了验证这一假设，PI 将使用涉及 PS 组装和吸附研究的组合方法。然后，这些发现将转化为 3D 水凝胶系统，通过自下而上的自组装方法生产，将使用三种新兴污染物模型来评估吸附能力和性能。四环素（一种抗生素）、布洛芬（一种镇痛剂）和 2,4-二氯苯氧基乙酸（一种除草剂）将通过以下具体目标进行测试：1) 阐明 PS 在自组装过程中相互作用的性质；了解组成和表面功能对 PS 组装膨胀和超分子结构的作用，3) 研究 3D 结构中 PS 自组装的不同途径，以及4）揭示超分子结构、组成和表面对PS组件整体吸附能力的影响。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

A review on lignocellulose chemistry, nanostructure, and their impact on interfacial interactions for sustainable products development

木质纤维素化学、纳米结构及其对可持续产品开发界面相互作用的影响综述

• DOI: 10.1007/s10853-022-07992-1
• 发表时间: 2022-12-09
• 期刊: Journal of Materials Science
• 影响因子: 4.5
• 作者: María C. Iglesias;Diego Gomez;V. Davis;M. Peresin
• 通讯作者: M. Peresin

Simple functionalization of cellulose beads with pre-propargylated chitosan for clickable scaffold substrates

使用预炔丙基化壳聚糖对纤维素珠进行简单功能化，用于可点击支架基材

• DOI: 10.1007/s10570-021-03905-8
• 发表时间: 2021-05-22
• 期刊: Cellulose
• 影响因子: 5.7
• 作者: Diego Gomez;Ilari Filpponen;Javier A. Hern;ez;ez;M. Waters;M. Auad;Leena‐Sisko Johansson
• 通讯作者: Leena‐Sisko Johansson

Development of a β-cyclodextrin-chitosan polymer as active coating for cellulosic surfaces and capturing of microcystin-LR

开发β-环糊精-壳聚糖聚合物作为纤维素表面的活性涂层并捕获微囊藻毒素-LR

• DOI: 10.1016/j.surfin.2022.102192
• 发表时间: 2022-10
• 期刊: Surfaces and Interfaces
• 影响因子: 6.2
• 作者: Gomez;Filpponen, Ilari;Vega Erramuspe, Iris Beatriz;Johansson, Leena;Mori, María Fernanda;Babu, R. Jayachandra;Waters, Matthew N.;Peresin, Maria S.
• 通讯作者: Peresin, Maria S.

The Applicability of Cellulose — Tara Gum Composite Hydrogels as Dye Capture Adsorbents

纤维素与塔拉胶复合水凝胶作为染料捕获吸附剂的适用性

• DOI: 10.1007/s11270-022-05818-z
• 发表时间: 2022-08-01
• 期刊: Water, Air, & Soil Pollution
• 作者: Diego Gomez;S. Ponce;M. Peresin
• 通讯作者: M. Peresin

Fabrication of aerogels from cellulose nanofibril grafted with β-cyclodextrin for capture of water pollutants

用β-环糊精接枝纤维素纳米纤维制备气凝胶，用于捕获水污染物

• DOI: 10.1007/s10934-021-01109-w
• 发表时间: 2021-12
• 期刊: Journal of Porous Materials
• 影响因子: 2.6
• 作者: Gomez;Reynolds, Autumn Marie;Johansson, Leena;Burnett, Daniel J.;Ramapuram, Jayachandra Babu;Waters, Matthew Neal;Vega Erramuspe, Iris Beatriz;Peresin, Maria Soledad
• 通讯作者: Peresin, Maria Soledad