Exploring the genomics of convergent snout elongations in deep-sea fishes

探索深海鱼类会聚口鼻伸长的基因组学

基本信息

批准号：
2015404
负责人：
Dahiana Arcila
金额：
$ 30.01万
依托单位：
University of Oklahoma Norman Campus
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2020
资助国家：
美国
起止时间：
2020-06-15 至 2024-05-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=2015404&HistoricalAwards=false
关键词：
Exploring genomics convergent snout elongations

项目摘要

Explaining how similar traits have independently evolved in distantly related organisms is a central goal of evolutionary biology. Among vertebrates, fishes are one of the few evolutionary systems that provide repeated cases of adaptation to deep-sea marine environments, one of the most extreme and underexplored environments on earth. Transitions from shallow to deep-sea habitats have occurred multiple times, resulting in a variety of remarkable adaptations, from the presence of bioluminescence and small body size to a diverse array of morphological specializations. However, detailed comparative studies investigating the origin and genomic bases of specialized phenotypic novelties that have repeatedly appeared in the deep-sea continue to be poorly understood. This project aims to develop a comparative approach to study convergent morphological evolution and its underlying ecological and genomic bases in the deep-sea spikefishes (Triacanthodidae, Tetraodontiformes), which are distributed around the tropical and temperate upper slopes of the world’s oceans.Spikefishes provide an outstanding system for investigating convergent evolution as lineages in the group have independently evolved at least twice the most extreme tubular snout elongation in the Fish Tree of Life, have some of the smallest vertebrate genomes, and included well-preserved fossil species from the Eocene and Oligocene. The integration of state-of-the-art genomic and morphological data with the study of extant and fossil species will allow new ways of exploring convergent morphological evolution in a genomic and ecological framework. Moreover, understanding the determinants of deep-sea convergence at the molecular level has the potential to inform general principles of adaptation and morphological predictivity along ocean depth gradients. Overall, this project will contribute whole-genome resequencing data, CT-scans for extant and fossil taxa, and a well-resolved phylogeny of triacanthodids and allies. This project will also provide online videos, tutorials, interactive apps, museum exhibits, undergraduate and graduate training, and a series of integrative research papers exploring the links between phenotype and genotype and the associations of genomic regions involved in morphological adaptations in fishes.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

解释在明显相关的生物中独立发展的类似特征是进化生物学的核心目标。在脊椎动物中，鱼类是为数不多的进化系统之一，可反复适应深海海洋环境，这是地球上最极端和最不受欢迎的环境之一。从浅层到深海栖息地的过渡已经发生了多次，从而导致了各种显着的适应，从生物发光和体积小到小型形态学专长的潜水员阵列。但是，研究了深入海上反复出现的专业表型新颖性的起源和基因组基础的详细比较研究，对此仍知之甚少。该项目旨在开发一种比较方法来研究收敛的形态进化及其在深海尖峰鱼（Triacanthodidae，Tetraodontiformes）中的基本生态和基因组基础，它们分布在热带和温度的上段围绕世界的热带和温度上段。生命的鱼树中的鼻伸长，具有一些最小的脊椎动物基因组，并包括始新世和渐新世的保存完好的化石物种。最先进的基因组和形态学数据与扩展物种和化石物种的研究的整合将允许在基因组和生态框架中探索融合形态演化的新方法。此外，了解分子水平的深海收敛的决定者具有为沿海洋深度梯度沿海深度梯度的适应性和形态预测性的一般原则提供的潜力。总体而言，该项目将贡献全基因组重新陈述数据，用于扩展和化石分类单元的CT扫描，以及三角形thodids and Allies的完善系统发育。该项目还将提供在线视频，教程，互动应用程序，博物馆展览，本科和研究生培训，以及一系列集成的研究论文探索了表型与基因型与基因型之间的联系以及与FISH的智力梅有良好的依从性的依从性。标准。