SBIR Phase I: Rapid Design and Prototyping System for Lab-On-Chip Devices

SBIR 第一阶段：片上实验室设备的快速设计和原型系统

• 批准号: 2014688
• 负责人: Joshua Gomes
• 金额: $ 22.5万
• 依托单位: Parallel Fluidics, Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-01 至 2021-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2014688&HistoricalAwards=false
• 关键词: SBIR; Phase; Rapid; Design; Prototyping

The broader impact/commercial impact of this Small Business Innovation Research (SBIR) Phase I project is to reduce cost and increase accuracy of solutions for the healthcare industry, including point-of-care diagnostics, therapeutics, and drug development, by enabling new lab-on-chip technologies. These technologies rely on microfluidic devices, small plastic parts that automatically and efficiently conduct scientific experiments with tiny volumes of liquid samples. Point-of-care devices can have a particularly profound impact on underserved communities by allowing access to testing otherwise unavailable due to cost and resource issues. The proposed system will decrease the time and expense required to develop technologies addressing these challenges. This SBIR Phase I project addresses the speed of lab-on-chip development through three main technical innovations: 1) A library of microfluidic features for design of microfluidic parts; 2) A rapid tooling system rapidly producing microfluidic molds; and 3) The macro-to-micro interface where lab-on-chip devices connect to the outside world. The proposed project will create an automated system to quickly and reliably connectorize microfluidic devices, increasing reliability and ease of use. The performance goal is a complete lab-on-chip prototyping system providing fully functional devices in less than a week.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项小型企业创新研究（SBIR）I阶段项目的更广泛的影响/商业影响是通过启用新实验室来降低医疗保健行业解决方案的成本和提高解决方案的准确性，包括护理点诊断，治疗和药物开发 - 芯片技术。这些技术依赖于微流体设备，这些塑料零件会自动有效地使用微量的液体样品进行科学实验。通过允许由于成本和资源问题，可以访问其他无法获得的测试，可以通过允许测试来对未服务的社区产生特别深远的影响。拟议的系统将减少开发解决这些挑战的技术所需的时间和费用。 SBIR I期项目通过三个主要技术创新来解决实验室芯片开发的速度：1）微流体设计的微流体特征库； 2）快速产生微流体模具的快速工具系统； 3）宏到微接口，其中实验室芯片设备连接到外界。拟议的项目将创建一个自动化系统，以快速可靠地连接微流体设备，从而提高可靠性和易用性。绩效目标是一个完整的芯片实验室原型制度系统，可在不到一周的时间内提供功能齐全的设备。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子优点和更广泛的影响评估的评估来通过评估来提供支持的。