SBIR Phase II: Novel Field Drug Test System for Law Enforcement

SBIR 第二阶段：用于执法的新型现场药物测试系统

• 批准号: 1951074
• 负责人: David Nash
• 金额: $ 74.99万
• 依托单位: IDEM, LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-01 至 2023-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1951074&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Novel; Field

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to develop technology that will improve law enforcement (LE) effectiveness in combatting the U.S. illegal drug epidemic, which contributed to over 67,000 drug overdose deaths in 2018. An affordable, effective field drug test system, superior to conventional color test kits and Raman-based test systems, would address this challenge, particularly because the widely used color test kits are outdated, hazardous, and susceptible to a high false positive rate. This novel drug test system will improve the accuracy, reliability, ease of use, safety, and affordability of field drug identification and permit data analysis that will help LE reduce the supply of dangerous drugs from the communities they serve. This innovation has the potential to expand into other markets, including medical diagnostics and environmental analysis.This Small Business Innovation Research (SBIR) Phase II project will implement a novel system for on-site presumptive drug testing and collection of drug intelligence for LE. Conventional color tests are inaccurate and highly flawed, often resulting in failure to accurately detect common drugs and novel drug analogues as they are introduced into the illegal substance market. Commercially available handheld devices that utilize Raman spectroscopy are superior to color test but are too expensive for local and state LE agencies to widely adopt. The research objectives involve further developing a system that leverages photoluminescence spectroscopy in a low-cost handheld spectrometer, a sampling device that uses a drug-indicating chemosensor, and software that consists of a mobile app and cloud-based technology to help identify illegal substances and specific drug signatures. The anticipated technical results will be the optimization of the handheld spectrometer design and drug-sampling device, identification of new photoluminescent chemosensors for controlled substances, and software to enhance the accuracy of the sample data analysis. This system will establish tools for forensic analysis of drug signatures and regional trends in illegal drug trafficking.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项小型企业创新研究（SBIR）第二阶段项目的更广泛的影响/商业潜力是开发技术，将提高执法（LE）在打击美国非法药物流行方面的有效性（LE）有效性，该流行病在2018年造成了67,000多种药物过量死亡。危险，容易受到高误报率的影响。这种新颖的药物测试系统将提高现场药物识别的准确性，可靠性，易用性，安全性和可负担性，并允许数据分析，这将有助于减少他们所服务社区的危险药物的供应。这项创新有可能扩展到其他市场，包括医学诊断和环境分析。这项小型企业创新研究（SBIR）第二阶段项目将实施一个新型系统，用于现场推定药物测试和LE的药物智能收集。常规的颜色测试不准确且有缺陷，通常导致未能准确检测到常见药物和新型药物类似物，因为它们被引入非法药物市场。利用拉曼光谱法的市售手持设备优于颜色测试，但对于本地和州LE代理商来说太昂贵了，无法广泛采用。研究目标涉及进一步开发一种系统，该系统利用低成本手持式光谱仪中利用光致发光光谱，这是一种使用药物鉴定化学传感器的采样设备，以及由基于移动应用程序和基于云的技术组成的软件，以帮助识别非法物质和特定药物签名。预期的技术结果将是手持光谱仪设计和药物采样设备的优化，对受控物质的新光致发光化学传感器的识别以及可提高样品数据分析准确性的软件。 该系统将建立对非法贩运药物特征和区域趋势进行法医分析的工具。该奖项反映了NSF的法定任务，并使用基金会的知识分子优点和更广泛的影响审查标准，被认为值得通过评估来提供支持。