Collaborative Research: SG: Clonality and the scope for adaptation in heterogeneous environments

合作研究：SG：克隆性和异构环境中的适应范围

• 批准号: 1923513
• 负责人: Robert Holt
• 金额: $ 3.76万
• 依托单位: University of Florida
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-15 至 2024-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1923513&HistoricalAwards=false
• 关键词: Collaborative; Research; SG; Clonality; scope

All species exist in a variety of environments. How a species adapts across those environments determines its survival in a particular location. This also determines the species range over time. The type of reproduction shown by an organism can have profound consequences for that adaptation across a varied landscape. One key reproductive mode, partial clonality, which includes both asexual reproduction, and sexual reproduction, is found in many organisms. These include species that influence many important ecosystems functions. Partial clonality is also found in many pathogens, pests, and invasive species. This research will develop mathematical models that explore how partial clonality and local environmental variation interact to shape the evolution of such species. The results of this research will help identify key aspects of populations that make them especially vulnerable to changing environmental conditions, leading to population decline and even extinction. Conversely, factors that allow populations to more easily adapt to new environments will also be determined. An important impact of this work is its applicability to our understanding of invasive species and emerging infectious diseases. Broader impacts also include increased mathematical literacy and a better understanding of the linkages between the biological sciences, mathematics, and statistics for both graduate and undergraduate students trained under this project.This study will explore the differences in the average selective regime experienced by clonal verses sexual offspring and how that may influence realized patterns of adaptation across a variable landscape. Of particular interest is the influence on genomic diversity, and a population's ability to persist under environmental change. Two complementary approaches will be utilized to address these complexities: (1) analytical models combining stage-structured life histories and phenotypic evolution and (2) individual-based forward-time simulation models allowing for consideration of important aspects of stochasticity in both evolution and demography will be applied. Together these two modeling methods will clarify the integrated effect of reproductive mode and variable selective environment in shaping the dynamics of speciesThis award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

所有物种都存在于多种环境中。物种如何在这些环境中适应其在特定位置的生存。这也决定了物种的范围。生物体所示的繁殖类型可能会对各种景观的适应产生深远的影响。在许多生物体中都发现了一种关键的生殖模式，包括无性繁殖和有性繁殖的部分克隆性。这些包括影响许多重要生态系统功能的物种。在许多病原体，害虫和入侵物种中也发现了部分克隆性。这项研究将开发数学模型，以探讨部分克隆性和局部环境变化如何相互作用以塑造这种物种的演变。这项研究的结果将有助于确定人口的关键方面，使他们特别容易受到改变的环境状况的影响，从而导致人口下降甚至灭绝。相反，还将确定允许种群更容易适应新环境的因素。这项工作的一个重要影响是它适用于我们对入侵物种和新兴传染病的理解。更广泛的影响还包括提高数学素养以及对根据该项目培训的研究生和本科生的生物科学，数学和统计学之间的联系的更好理解后代以及这可能会影响可变景观中实现的适应模式。特别感兴趣的是对基因组多样性的影响，以及人口在环境变化下持续存在的能力。将利用两种互补方法来解决这些复杂性：（1）结合阶段结构的生活历史和表型进化的分析模型，以及（2）基于个体的远期时间仿真模型，允许考虑进化和人口统计学中随机性的重要方面将被应用。这两种建模方法一起将阐明生殖模式和可变选择性环境在塑造SpeciestHis奖的动态方面的综合效果，反映了NSF的法定任务，并被认为是值得通过基金会的智力优点和更广泛的影响来通过评估来支持的。

项目成果

Environmental fluctuations dampen the effects of clonal reproduction on evolutionary rescue

环境波动削弱了克隆繁殖对进化救援的影响

• DOI: 10.1111/jeb.13778
• 发表时间: 2021
• 期刊: Journal of Evolutionary Biology
• 影响因子: 2.1
• 作者: Peniston, James H.;Barfield, Michael;Holt, Robert D.;Orive, Maria E.
• 通讯作者: Orive, Maria E.