Digitization TCN: Collaborative Research: oVert: Open Exploration of Vertebrate Diversity in 3D

数字化 TCN:合作研究:oVert:3D 脊椎动物多样性的开放探索

基本信息

  • 批准号:
    1702263
  • 负责人:
  • 金额:
    $ 18.93万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-09-01 至 2022-12-31
  • 项目状态:
    已结题

项目摘要

The oVert (openVertebrate) Thematic Collection Network (TCN) will generate and serve high-resolution digital three-dimensional (3D) data for internal anatomy across vertebrate diversity. Via a network of digitization centers across the US, more than 20,000 fluid-preserved specimens representing over 80% of the living genera of vertebrates will be CT-scanned. This will provide broad coverage for exploration and research on all major groups of vertebrates. Contrast-enhanced scans will be generated that reveal soft tissues and organs. This collection of digital imagery and three-dimensional volumes will be open for exploration, download, and use to address questions related to the discovery of new species, documenting patterns of anatomical diversity and growth, and testing hypotheses of function and evolution. The resource will provide unprecedented global access to valuable specimens in US museum collections and will develop best practices and guidelines for high-throughput CT-scanning, including efficient workflows, preferred resolutions, and archival formats that optimize the variety of downstream applications. Museum specialists will be trained on the generation, curation, and distribution of 3D data, researchers in using 3D anatomical data, and high school and undergraduate students in the tools for creating 3D anatomical models. To drive the use of these digital specimens by K-12 STEM educators, teacher-driven workshops that generate freely available lesson plans focused on specific science standards that are based on digital and printed 3D models of specimens in US museum collections.Data generated by oVert will serve as a catalyst for diverse research projects focused on understanding the vertebrate morphological diversity and will dramatically increase the accessibility of specimens housed in US scientific collections. These anatomical phenotypes represent a common currency that facilitates integration across the fields of taxonomy, evolution, developmental biology, comparative physiology, functional anatomy, paleontology, and ecology. The x-ray computed tomography (CT) scanning gemerates high-resolution digital anatomical data, represented as both 2D image stacks and 3D volumes and surfaces. With these 3D digital specimens, US and international research communities will be able to (1) diagnose, describe, and infer patterns of relationships among both living and extinct vertebrates, (2) test hypotheses of morphological evolution such as patterns of disparity, modularity, and phenotype-environment correlations, (3) develop structure-function models for testing hypotheses about morphological adaptations related to, e.g., feeding and locomotion, and (4) explore relationships between brain and nervous system anatomy and both sensory and musculoskeletal function. The 3D data will be distributed globally through MorphoSource, an on-line data repository for 3D biological specimen data, which will capture standardized metadata, ingest legacy data from previous and existing projects, and will supply media information to data aggregators including iDigBio (www.idigbio.org). Training workshops, both on-site at participating institutions and national society meetings of scientists and educators are planned to foster innovation and capabilities for users of 3D image data.
公开的(开放膜)主题收集网络(TCN)将生成并为跨脊椎动物多样性的内部解剖结构生成并提供高分辨率数字三维(3D)数据。 通过整个美国的数字化中心网络,将ct扫描占20,000多种占脊椎动物生命属的水平超过80%的标本。 这将为所有主要脊椎动物群体探索和研究提供广泛的覆盖范围。 将产生对比增强的扫描,以显示软组织和器官。 该数字图像和三维卷的集合将开放,用于探索,下载和用于解决与发现新物种有关的问题,记录解剖学多样性和增长的模式以及测试功能和进化的假设。 该资源将在美国博物馆收藏中提供前所未有的全球对有价值标本的访问,并将为高通量CT扫描的最佳实践和准则提供最佳实践和准则,包括高效的工作流程,首选分辨率和档案格式,以优化各种下游应用程序。 博物馆专家将接受3D数据的一代,策划和分布的培训,研究人员使用3D解剖学数据以及高中和本科生,用于创建3D解剖模型的工具。 为了推动K-12 STEM教育工作者使用这些数字标本的使用,以教师为驱动的研讨会,这些研讨会可免费提供基于美国博物馆集合中的数字和印刷3D标本的特定科学标准。这些解剖表型代表了一种共同的货币,可促进分类,进化,发育生物学,比较生理学,功能解剖学,古生物学和生态学领域的整合。 X射线计算机断层扫描(CT)扫描宝石可高分辨率数字解剖数据,以2D图像堆栈和3D体积和表面表示。 借助这些3D数字标本,美国和国际研究社区将能够(1)诊断,描述和推断生命和灭绝脊椎动物之间关系模式的模式,(2)测试形态进化的假设,例如,差异,模块化,模块化和表型 - 环境互相关的模型,(3)对结构互动的模型,(3)与测试相关的模型。运动和(4)探索大脑与神经系统解剖结构以及感觉和肌肉骨骼功能之间的关系。 3D数据将通过Morphosource在全球分布,Morphosource是3D生物标本数据的在线数据存储库,该数据将捕获标准化的元数据,以前和现有项目的摄入遗产数据,并将向包括IDIGBIO(www.idigbio.org)在内的数据聚合器提供媒体信息。 培训讲习班,即参与机构的现场和科学家和教育工作者的国家社会会议,以促进3D图像数据用户的创新和能力。

项目成果

期刊论文数量(3)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Descriptions of five new species of the salamander genus Chiropterotriton (Caudata: Plethodontidae) from eastern Mexico and the status of three currently recognized taxa
  • DOI:
    10.7717/peerj.8800
  • 发表时间:
    2020-05-26
  • 期刊:
  • 影响因子:
    2.7
  • 作者:
    Parra Olea,Gabriela;Garcia-Castillo,Mirna G.;Wake,David B.
  • 通讯作者:
    Wake,David B.
3D scanning of antique glass by combining photography and computed tomography
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James Hanken其他文献

Small molecule-mediated “phenotypic engineering” reveals a role for retinoic acid in anuran gut evolution
  • DOI:
    10.1016/j.ydbio.2008.05.109
  • 发表时间:
    2008-07-15
  • 期刊:
  • 影响因子:
  • 作者:
    Stephanie Bloom;Carlos Infante;Anne Everly;James Hanken;Nanette Nascone-Yoder
  • 通讯作者:
    Nanette Nascone-Yoder
Molecular anatomy of the developing limb bud in the coqúi frog, <em>Eleutherodactylus coqui</em>
  • DOI:
    10.1016/j.ydbio.2011.05.549
  • 发表时间:
    2011-08-01
  • 期刊:
  • 影响因子:
  • 作者:
    Joshua Gross;Ryan Kerney;James Hanken;Clifford Tabin
  • 通讯作者:
    Clifford Tabin
The evolution of appendicular muscles formation by migrating muscle precursors in vertebrates: perspectives from the catshark
脊椎动物通过迁移肌肉前体形成附肢肌肉的进化:来自猫鲨的观点
  • DOI:
  • 发表时间:
    2017
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Ingrid R Cordeiro;Kaori Kabashima;Haruki Ochi;Keijiro Munakata;Mara Laslo;James Hanken;Mikiko Tanaka;Mikiko Tanaka;Eri Okamoto
  • 通讯作者:
    Eri Okamoto
Environmental oxygen levels and interdigital cell death in tetrapods
环境氧气水平和四足动物的指间细胞死亡
  • DOI:
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    11.8
  • 作者:
    Ingrid R Cordeiro;Kaori Kabashima;Haruki Ochi;Keijiro Munakata;Chika Nishimori;Mara Laslo;James Hanken;Mikiko Tanaka
  • 通讯作者:
    Mikiko Tanaka
How somitic cells migrate into the axolotl limb bud and vertebrate appendicular muscle evolution
  • DOI:
    10.1016/j.ydbio.2011.05.572
  • 发表时间:
    2011-08-01
  • 期刊:
  • 影响因子:
  • 作者:
    Elizabeth Sefton;Nadine Piekarski;James Hanken
  • 通讯作者:
    James Hanken

James Hanken的其他文献

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{{ truncateString('James Hanken', 18)}}的其他基金

Creating a Novel Museum-Based Resource for Neuroscience: Mass whole-slide imaging of the R. Glenn Northcutt Collection of Comparative Vertebrate Neuroanatomy and Embryology
创建基于博物馆的新型神经科学资源:R. Glenn Northcutt 比较脊椎动物神经解剖学和胚胎学收藏品的大规模全幻灯片成像
  • 批准号:
    2122620
  • 财政年份:
    2021
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
Digitization TCN: Collaborative Research: Documenting marine biodiversity through Digitization of Invertebrate collections (DigIn)
数字化 TCN:合作研究:通过无脊椎动物收藏数字化记录海洋生物多样性 (DigIn)
  • 批准号:
    2001540
  • 财政年份:
    2020
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
Digitization TCN: Collaborative Research: Enhancing Access to Taxonomic and Biogeographical Data to Stem the Tide of Extinction of the Highly Imperiled Pacific Island Land Snails
数字化 TCN:合作研究:加强对分类学和生物地理数据的获取,以阻止高度濒危的太平洋岛屿蜗牛的灭绝浪潮
  • 批准号:
    1902188
  • 财政年份:
    2019
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
Dissertation Research: Evaluating the role of thyroid hormone in embryonic limb development in direct-developing frogs
论文研究:评估甲状腺激素在直接发育的青蛙胚胎肢体发育中的作用
  • 批准号:
    1701591
  • 财政年份:
    2017
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
DISSERTATION RESEARCH: Mutant models reveal latent developmental potential with roles in evolutionary change
论文研究:突变模型揭示了潜在的发展潜力及其在进化变化中的作用
  • 批准号:
    1600920
  • 财政年份:
    2016
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
Collaborative Research: Digitization TCN: InvertEBase: Reaching Back to See the Future: Species-rich Invertebrate Faunas Document Causes and Consequences of Biodiversity Shifts
合作研究:数字化 TCN:InvertEBase:回望未来:物种丰富的无脊椎动物区系记录生物多样性转变的原因和后果
  • 批准号:
    1401450
  • 财政年份:
    2014
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
Collaborative Research: ABI Development: Kurator: A Provenance-enabled Workflow Platform and Toolkit to Curate Biodiversity Data
协作研究:ABI 开发:Kurator:用于管理生物多样性数据的支持来源的工作流程平台和工具包
  • 批准号:
    1356438
  • 财政年份:
    2014
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
Filtered Push: Continuous Quality Control for Distributed Collections and Other Species-Occurrence Data.
过滤推送:分布式集合和其他物种出现数据的连续质量控制。
  • 批准号:
    0960535
  • 财政年份:
    2010
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
AToL: Collaborative Research: AmphibiaTree--An Integrated Phylogenetic and Bioinformatics Approach to the Tree of Amphibians
AToL:合作研究:AmphibiaTree——两栖动物树的综合系统发育和生物信息学方法
  • 批准号:
    0334846
  • 财政年份:
    2004
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Continuing Grant
Physical Renovation of the Herpetology Collection of the Museum of Comparative Zoology, Harvard University
哈佛大学比较动物学博物馆爬虫学藏品的物理翻新
  • 批准号:
    0096657
  • 财政年份:
    2001
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant

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中国汉族人群糖尿病肾病易感基因TCN2功能及致病机制研究
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相似海外基金

Collaborative Research: Digitization TCN: iDigBees Network, Towards Complete Digitization of US Bee Collections to Promote Ecological and Evolutionary Research in a Keystone Clade
合作研究:数字化 TCN:iDigBees 网络,实现美国蜜蜂收藏的完全数字化,以促进重点进化枝的生态和进化研究
  • 批准号:
    2216936
  • 财政年份:
    2022
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
Collaborative Research: Digitization TCN: iDigBees Network, Towards Complete Digitization of US Bee Collections to Promote Ecological and Evolutionary Research in a Keystone Clade
合作研究:数字化 TCN:iDigBees 网络,实现美国蜜蜂收藏的完全数字化,以促进重点进化枝的生态和进化研究
  • 批准号:
    2216932
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    2022
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
Collaborative Research: Digitization TCN: iDigBees Network, Towards Complete Digitization of US Bee Collections to Promote Ecological and Evolutionary Research in a Keystone Clade
合作研究:数字化 TCN:iDigBees 网络,实现美国蜜蜂收藏的完全数字化,以促进重点进化枝的生态和进化研究
  • 批准号:
    2216930
  • 财政年份:
    2022
  • 资助金额:
    $ 18.93万
  • 项目类别:
    Standard Grant
Collaborative Research: Digitization TCN: iDigBees Network, Towards Complete Digitization of US Bee Collections to Promote Ecological and Evolutionary Research in a Keystone Clade
合作研究:数字化 TCN:iDigBees 网络,实现美国蜜蜂收藏的完全数字化,以促进重点进化枝的生态和进化研究
  • 批准号:
    2216934
  • 财政年份:
    2022
  • 资助金额:
    $ 18.93万
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    Standard Grant
Collaborative Research: Digitization TCN: iDigBees Network, Towards Complete Digitization of US Bee Collections to Promote Ecological and Evolutionary Research in a Keystone Clade
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