DISSERTATION RESEARCH: Integrating Physiology and Genomics to Test for Local Adaptation in a Montane Ectotherm
论文研究:整合生理学和基因组学来测试山地变温动物的局部适应
基本信息
- 批准号:1701231
- 负责人:
- 金额:$ 2.01万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-06-15 至 2019-05-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This project will investigate the processes determining color and size differences between western fence lizards occurring at high versus low elevations on mountains in California. High elevation lizards are darker and larger than low elevation lizards. Such differences in traits within a species are generally assumed to be genetically based and a result of adaptation to local environments. However, phenotypic differences can also result from the effects of different environmental conditions on development. The researchers will use a combination of physiological experiments and genomic analyses to identify whether color and size differences in western fence lizards are a consequence of natural selection or phenotypic plasticity. Results will provide critical insights into the role and evolutionary advantages of environmentally dependent phenotypic differences in heterogeneous environments. In addition, the project includes day-long educational workshops targeting young girls interested in STEM fields and development of an interactive exhibit on lizards for a local museum.This study focuses on a phenotypic cline in the western fence lizard (Sceloporus occidentalis) along an elevational gradient in the Sierra Nevada Mountains of California. By combining techniques from genomics, functional ecology, and transcriptomics, this research will develop a comprehensive picture of the origin and function of high elevation phenotypes in western fence lizards. The researchers plan to evaluate the influence of temperature and day length on juvenile phenotypes, and to identify candidate genomic regions implicated in phenotypic differentiation. Juvenile lizards will be reared in a laboratory common garden experiment with treatments that mimic conditions at high and low elevation. This experimental design will decouple the genetic and environmental constituents of phenotype, and also shed light on the functional implications of trait differences. By comparing gene expression profiles of lizards reared in native and non-native conditions, fixed and plastic responses to environmental conditions at both organismal and genomic levels will be identified.
该项目将调查确定在加利福尼亚州山区高海拔与低海拔的西部栅栏蜥蜴之间的颜色和尺寸差异的过程。高海拔蜥蜴比低海拔蜥蜴更暗且大。通常认为,物种内部特征的这种差异是基于遗传的,并且是适应局部环境的结果。但是,表型差异也可能是由于不同环境条件对发展的影响。研究人员将使用生理实验和基因组分析的结合来确定西部栅栏蜥蜴的颜色和大小差异是自然选择还是表型可塑性的结果。结果将提供有关在异质环境中环境依赖的表型差异的作用和进化优势的关键见解。此外,该项目还包括为期一天的教育研讨会,针对对STEM领域感兴趣的年轻女孩以及在当地博物馆的蜥蜴上开发的互动展览。这项研究着重于西方栅栏蜥蜴(Sceloporus occidentalis)沿着内里拉山脉山脉山脉的高度梯度。通过结合基因组学,功能生态学和转录组学的技术,这项研究将对西方栅栏蜥蜴高升高表型的起源和功能进行全面了解。研究人员计划评估温度和白天对少年表型的影响,并确定与表型分化有关的候选基因组区域。少年蜥蜴将在实验室通用花园实验中饲养,并通过模仿高海拔的治疗方法。该实验设计将使表型的遗传和环境成分解脱,并阐明性状差异的功能意义。通过比较在天然和非本地条件下饲养的蜥蜴的基因表达谱,将确定对生物和基因组水平的环境条件的固定和塑性反应。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

暂无数据
数据更新时间:2024-06-01
Adam Leache的其他基金
Collaborative Research: Species delimitation in North American lizards
合作研究:北美蜥蜴的物种界定
- 批准号:20237232023723
- 财政年份:2020
- 资助金额:$ 2.01万$ 2.01万
- 项目类别:Standard GrantStandard Grant
Collaborative Research: Epidermal gland evolution and the origins of structural and chemical signaling diversity
合作研究:表皮腺进化以及结构和化学信号多样性的起源
- 批准号:18558451855845
- 财政年份:2019
- 资助金额:$ 2.01万$ 2.01万
- 项目类别:Continuing GrantContinuing Grant
DISSERTATION RESEARCH: Investigating the Joint Effects of Phylogeny and Adaptation on Phenotypic Variation at a Continental Scale (Serpentes:Thamnophis)
论文研究:研究系统发育和适应对大陆尺度表型变异的联合影响(蛇类:Thamnophis)
- 批准号:16008841600884
- 财政年份:2016
- 资助金额:$ 2.01万$ 2.01万
- 项目类别:Standard GrantStandard Grant
DISSERTATION RESEARCH: Hybrid zone formation and comparative genomic divergences in South American lizards (Iguania: Liolaemidae)
论文研究:南美蜥蜴(鬣蜥:Liolaemidae)的杂交区形成和比较基因组差异
- 批准号:15009331500933
- 财政年份:2015
- 资助金额:$ 2.01万$ 2.01万
- 项目类别:Standard GrantStandard Grant
DISSERTATION RESEARCH: Investigating the genomic structure of speciation: a comparative approach using wagtails (Aves: Motacilla)
论文研究:研究物种形成的基因组结构:使用鹡鸰的比较方法(Aves:Motacilla)
- 批准号:15011311501131
- 财政年份:2015
- 资助金额:$ 2.01万$ 2.01万
- 项目类别:Standard GrantStandard Grant
COLLABORATIVE RESEARCH: Mechanisms of Diversification in West African Rainforest Amphibians and Reptiles
合作研究:西非雨林两栖动物和爬行动物的多样化机制
- 批准号:14560981456098
- 财政年份:2015
- 资助金额:$ 2.01万$ 2.01万
- 项目类别:Standard GrantStandard Grant
DISSERTATION RESEARCH: Comparative Phylogeography and Thermal Ecology of Puerto Rican Anoles
论文研究:波多黎各安乐蜥的比较系统发育地理学和热生态学
- 批准号:15011341501134
- 财政年份:2015
- 资助金额:$ 2.01万$ 2.01万
- 项目类别:Standard GrantStandard Grant
Resolving rapid radiations and recent speciation in North American spiny lizards (Sceloporus)
解决北美刺蜥蜴(Sceloporus)的快速辐射和近期物种形成问题
- 批准号:11446301144630
- 财政年份:2012
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NSF Postdoctoral Research Fellowship in Biology for FY 2008
2008 财年 NSF 生物学博士后研究奖学金
- 批准号:08054550805455
- 财政年份:2008
- 资助金额:$ 2.01万$ 2.01万
- 项目类别:FellowshipFellowship
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