Hydroidfest: A Workshop on Hydroid Biology, September 23-25, 2016, Bodega Bay, CA

Hydroidfest：水螅生物学研讨会，2016 年 9 月 23-25 日，加利福尼亚州博德加湾

• 批准号: 1637184
• 负责人: Celina Juliano
• 金额: $ 2.18万
• 依托单位: University of California-Davis
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-15 至 2017-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1637184&HistoricalAwards=false
• 关键词: Hydroidfest; Workshop; Hydroid; Biology; September

"Hydroidfest 2016" will take place September 23-25, 2016 at the Bodega Bay Marine Laboratory in Bodega Bay, California. This meeting will focus on hydroids, a group of aquatic animals with untapped, but exciting potential for developmental biology and neurobiology research. Major breakthroughs are made using model laboratory animals (e.g. mouse or fruit fly) to understand basic concepts that will apply to many or all animals. Traditionally, only a small number of model animals are used by researchers due to the limitation of experimental techniques in non-model animals; this can lead to biases and knowledge gaps. Recent breakthroughs in technology allow a great expansion in the number of animal models, which will dramatically increase insight into fundamental biological processes. One such group of interesting, but understudied animals are hydroids. A small but growing number of scientists have used hydroids to make fundamental discoveries and with newly developed technologies are now poised to make major breakthroughs. This burgeoning hydroid community will meet at "Hydroidfest 2016" to discuss new ideas, learn about new technologies, form new collaborations, and foster community growth. The meeting will focus particularly on encouraging interactions between experienced scientists and new trainees, with an emphasis on increasing diversity. This meeting will have a very positive effect on the hydroid research community and will be established as a biennial event. Hydroids are exciting laboratory models for making fundamental discoveries in many areas of biology, including development and neurobiology: 1) They have a simple and well-understood body plan that has been key to understanding developmental concepts such as Wnt signaling; 2) They have an informative phylogenetic position: they are in the clade that is sister to bilaterians and therefore discoveries made often reflect deeply conserved eukaryotic processes; 3) Hydroids are transparent, which greatly facilitates live imaging, particularly for recording the activity of the nervous system; 4) The study of colonial hydroids (e.g. Hydractinia) offers insights into the early evolution of metazoans and the origins of self-/non-self-recognition, and; 5) Hydroids are a great model for stem cell biology and aging, as Hydra has an estimated lifespan upwards of 3000 years. These topics will be the major scientific focus of this meeting, with an emphasis on bringing new technological approaches to bear on the biology of hydroids, particularly in combination with traditional techniques such as grafting and aggregating cell suspensions into new animals. Three technology workshops led by experts outside of the hydroid community will focus on: 1) Live imaging; 2) Genome editing with CRISPR-Cas9, and; 3) Collecting and analyzing genomic and transcriptomic data. This exciting and informative scientific program will enormously benefit the community of scientists working on hydroids.

“ HydroidFest 2016”将于2016年9月23日至25日在加利福尼亚Bodega Bay的Bodega Bay Marine Laboratory举行。 这次会议将集中于一群尚未开发但令人兴奋的发育生物学和神经生物学研究潜力的水生动物。 使用模型实验室动物（例如小鼠或果蝇）进行重大突破，以了解适用于许多或所有动物的基本概念。 传统上，由于非模型动物的实验技术的局限性，研究人员仅使用了少量模型动物。这可能导致偏见和知识差距。 技术的最新突破可以大大扩展动物模型，这将极大地增加对基本生物学过程的见解。 一组有趣但正在研究的动物是水型动物。 少数但越来越多的科学家已经使用水型来做出基本发现，并且随着新开发的技术，现在已经准备好实现重大突破。 这个新兴的水力社区将在“ HydroidFest 2016”上开会，讨论新的想法，了解新技术，形成新的合作和促进社区成长。 会议将特别关注鼓励经验丰富的科学家与新学员之间的互动，重点是增加多样性。 这次会议将对水力学研究社区产生非常积极的影响，并将作为两年一次的活动建立。 水型是令人兴奋的实验室模型，可在许多生物学领域（包括开发和神经生物学领域）进行基本发现：1）它们具有一个简单且宽容的身体计划，这是理解诸如Wnt信号之类的发展概念的关键； 2）他们具有信息性的系统发育地位：他们在分支机构中，这是双层妇女的姐妹，因此发现的发现经常反映出深厚保守的真核过程； 3）氢化体是透明的，它极大地促进了现场成像，特别是用于记录神经系统的活性； 4）对殖民地氢化殖民（例如Hydractinia）的研究提供了对后生动物早期演变和自我/非自我识别的起源的见解，以及； 5）氢化体是干细胞生物学和衰老的一个很好的模型，因为Hydra的寿命估计超过3000年。 这些主题将是这次会议的主要科学重点，重点是将新技术方法带入水力学的生物学上，尤其是与传统技术（例如接枝和将细胞悬浮液聚集到新动物中）的结合。 由Hydroid社区以外的专家领导的三个技术研讨会将重点关注：1）实时成像； 2）用CRISPR-CAS9进行基因组编辑，以及； 3）收集和分析基因组和转录组数据。 这项令人兴奋的信息科学计划将极大地使从事水力学的科学家社区受益。