MRI: Acquisition of an upgraded radio frequency console, a broadband nitrogen-cooled probe and an autosampler for a 400 MHz nuclear magnetic resonance (NMR) spectrometer

MRI：为 400 MHz 核磁共振 (NMR) 波谱仪采购升级的射频控制台、宽带氮冷探头和自动进样器

• 批准号: 1625340
• 负责人: William Dougherty
• 金额: $ 22.39万
• 依托单位: Susquehanna University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-15 至 2019-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1625340&HistoricalAwards=false
• 关键词: MRI; Acquisition; upgraded; radio; frequency

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor William Dougherty from Susquehanna University and colleagues Geneive Henry and Elizabeth Valentin have upgraded a 400 MHz Nuclear Magnetic Resonance (NMR) spectrometer by equipping it with a new radio frequency console, a broadband probe capable of operating between -100 and +150 degrees Centigrade and a 24-position autosampler. The upgraded electronics for the spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as those that allow study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. The acquired probe acts both as a broadband and high-field probe which increases sensitivity. This instrument is an integral part of teaching as well as research performed by undergraduate students via independent student research and traditional academic coursework.The award is aimed at enhancing research and education at all levels, especially in areas such as (a) understanding the influence chemical structure has on the redox properties of transition metal complexes; (b) studying the redox properties of first row transition metal complexes bearing sterically bulky trispyrazolylborate ligands and (c) isolating and spectroscopically characterizing natural products from Carex (grassy plants or sedge) and Hypericum species (herbaceous shrubs) growing in Pennsylvania.

凭借重大研究仪器计划 (MRI) 的这一奖项以及化学研究仪器计划 (CRIF) 的支持，萨斯奎哈纳大学的 William Dougherty 教授及其同事 Geneive Henry 和 Elizabeth Valentin 升级了 400 MHz 核磁共振 (NMR) 波谱仪为其配备了新的射频控制台、能够在 -100 至 +150 摄氏度之间运行的宽带探头以及 24 位自动进样器。光谱仪升级后的电子设备允许在各个领域进行研究，例如加速具有重大经济意义的化学反应的领域，以及允许研究生物学相关物种的领域。一般来说，核磁共振波谱是化学家阐明分子结构最强大的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液或固态分子之间相互作用的动力学。 这些核磁共振研究的结果对合成有机/无机化学、材料化学和生物化学产生影响。所采集的探头既可用作宽带探头，也可用作高场探头，从而提高了灵敏度。该仪器是本科生通过独立学生研究和传统学术课程进行的教学和研究的一个组成部分。该奖项旨在加强各个层面的研究和教育，特别是在以下领域：(a) 了解影响化学结构对过渡金属配合物氧化还原性能的影响； (b) 研究带有空间庞大的三吡唑基硼酸酯配体的第一行过渡金属配合物的氧化还原性质，以及 (c) 分离和光谱表征来自宾夕法尼亚州生长的苔草（草本植物或莎草）和金丝桃属物种（草本灌木）的天然产物。