MEETING: Evolutionary Endocrinology: Hormones as Mediators of Evolutionary Phenomena (SICB Symposium, January 5, 2016 in Portland, OR)

会议：进化内分泌学：激素作为进化现象的中介（SICB 研讨会，2016 年 1 月 5 日在俄勒冈州波特兰市）

• 批准号: 1539936
• 负责人: Robert Cox
• 金额: $ 1.47万
• 依托单位: University of Virginia Main Campus
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-01 至 2016-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1539936&HistoricalAwards=false
• 关键词: MEETING; Evolutionary; Endocrinology; Hormones; Mediators

This conference will bring together leading experts to explore the importance of hormones in evolutionary research. A central goal of modern biology is to understand the complex networks through which genes are translated into organisms. Historically, the field of endocrinology has played a large part in this endeavor by discovering the many pathways through which hormones regulate the behavior, development, and physiology of organisms. In parallel, the field of evolutionary biology has developed the statistical tools for predicting how both genes and organisms evolve in response to selection, as well as a variety of experimental techniques for testing these predictions. Yet, evolutionary biologists have rarely sought to incorporate hormones and endocrine pathways into evolutionary theory, and most endocrinologists still focus on a handful of "model organisms," providing relatively little evolutionary context for their mechanistic studies. With the increasing availability of genomic data from non-model species and the relative ease with which "next-generation" sequencing technologies now permit scientists to assess the roles of hormones in coordinating the expression of thousands of genes, these fields are ripe for synthesis under the emerging framework of Evolutionary Endocrinology. Held at the annual meeting of the Society for Integrative and Comparative Biology, this conference will bring together endocrinologists and evolutionary biologists to explore the many roles of hormones in mediating phenomena that are at the forefront of modern evolutionary research. It will establish SICB as the home for this emerging field while leveraging this society's diverse network of Divisions with complementary views (Comparative Endocrinology, Ecology & Evolution, Evolutionary Developmental Biology, Animal Behavior). The award will support symposium speakers who encompass a diverse mix of genders, career stages, focal species, endocrine pathways, and evolutionary phenomena. It will also support a complementary session by a similarly diverse lineup of students, postdocs and early career scientists, along with online resources and networking events designed to foster collaboration between these young investigators and established leaders in the field. Participants will each contribute a peer-reviewed article to a special issue of Integrative and Comparative Biology. Conference organizers will provide a synthetic overview and prospectus piece designed to identify and develop actionable strategies for a synthetic field of Evolutionary Endocrinology to emerge as a foundation for training the next generation of integrative scientists.

本次会议将汇集顶尖专家，探讨激素在进化研究中的重要性。现代生物学的一个中心目标是了解基因转化为生物体的复杂网络。从历史上看，内分泌学领域通过发现激素调节生物体的行为、发育和生理学的多种途径，在这一努力中发挥了重要作用。与此同时，进化生物学领域开发了用于预测基因和生物体如何响应选择而进化的统计工具，以及用于测试这些预测的各种实验技术。然而，进化生物学家很少试图将激素和内分泌途径纳入进化理论，大多数内分泌学家仍然关注少数“模式生物”，为他们的机制研究提供相对较少的进化背景。随着非模型物种基因组数据的可用性不断增加，以及“下一代”测序技术现在允许科学家相对容易地评估激素在协调数千个基因表达中的作用，这些领域的合成时机已经成熟。进化内分泌学的新兴框架。这次会议在综合与比较生物学学会年会上举行，将汇集内分泌学家和进化生物学家，探讨激素在介导现代进化研究前沿现象中的多种作用。它将把 SICB 打造成这个新兴领域的大本营，同时利用该协会多元化的部门网络和互补的观点（比较内分泌学、生态学与进化、进化发育生物学、动物行为）。该奖项将支持涵盖不同性别、职业阶段、焦点物种、内分泌途径和进化现象的研讨会演讲者。它还将支持由同样多样化的学生、博士后和早期职业科学家组成的补充会议，以及旨在促进这些年轻研究人员和该领域知名领导者之间合作的在线资源和网络活动。参与者每人将在《综合与比较生物学》特刊上发表一篇经过同行评审的文章。会议组织者将提供综合概述和招股说明书，旨在为进化内分泌学综合领域确定和制定可行的策略，作为培训下一代综合科学家的基础。

项目成果

Sex steroids as mediators of phenotypic integration, genetic correlations, and evolutionary transitions

性类固醇作为表型整合、遗传相关性和进化转变的中介

• DOI: 10.1016/j.mce.2019.110668
• 发表时间: 2020-02
• 期刊: Molecular and Cellular Endocrinology
• 影响因子: 4.1
• 作者: Cox; Robert M.
• 通讯作者: Robert M.