Collaborative Research: Actively Controllable Microfluidics with Film-Confined Redox-Magnetohydrodynamics: experiment and simulation

合作研究：薄膜限制氧化还原磁流体动力学主动可控微流体：实验和模拟

• 批准号: 1336722
• 负责人: Kakkattukuzhy Isaac
• 金额: $ 16.54万
• 依托单位: Missouri University of Science and Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1336722&HistoricalAwards=false
• 关键词: Collaborative; Research; Actively; Controllable; Microfluidics

Fritch/Isaac1336853/1336722Selective activation of redox-polymer-modified electrodes in a small volume in magnetic fields will be investigated to control microfluidics spatially and temporally. This new form of magnetohydrodynamics (MHD), as opposed to adding redox species to the solution or not adding them at all, defeats problems that hinder MHD from use in lab-on-a-chip (LOAC) devices. It allows higher currents with lower voltages, and thus, higher MHD forces and faster velocities without bubble formation or corrosion, faster response times, and compatibility with detectors and samples. MHD offers greater versatility over other micropumps, because flow can be programmed without redesigning channels of a device. An interdisciplinary, preexisting collaboration of investigators in Chemistry & Biochemistry at the Univ. of Arkansas and in Mechanical & Aerospace Engineering at Missouri Univ. of Science & Technology will perform the research.Intellectual Merit :Reduction/oxidation of chemical species confined to polymer films on electrodes creates an ionic current in solution. When at right angles to the magnetic field, the resulting MHD force causes fluid to flow there in the third dimension. Individually-addressable electrodes will be fabricated in desired patterns, polymer films will be polymerized and characterized by electrochemistry, electrodes will be activated with current and voltage in magnetic fields, and flow will be monitored by microbead movement in solution. The objectives are to (1) establish large coulombic capacity, fast response, and equivalent circuit models for redox-polymer films on electrodes, (2) control and maximize flow velocities, tune profiles, switch direction, and drive adjacent counter-flows using concentric disk-ring configurations of redox-polymer-modified electrodes perpendicular to a magnetic field, (3) sustain fluid flow by recharging redox-polymer films, and (4) use simulations to obtain spatial maps of ionic current density, MHD force density, and fluid velocities as a function of time, compare with experiment, and evaluate parameters that exceed experimental limits to better design redox-MHD microfluidic devices.Broader Impacts :The goal is to control microfluidics in a programmable way with far-reaching consequences toward products of interest to the public, such as hand-held, self-contained chemical analysis units for medical, environmental, and household uses. The interdisciplinary nature of the project enhances training of students involved in the research. Completed software modules will become available for testing and further evaluation to the scientific community free of charge. An outreach collaboration between science, math, and language arts teachers at The New School and mentors at the U of A and Missouri S&T will use MHD as a starting point to stimulate viral learning for middle school students on topics of forces and energy. Students will perform self-directed projects in collaboration with teachers and mentors, communicate results with videos using their own vocabulary and perspective, which they have scripted, edited, produced, and post them on the internet for public viewing and commentary. This approach is expected to bridge the gap between university research and middle school education, while simultaneously enhancing STEM education and educator development and increasing public scientific literacy and public engagement with science and technology.

Friitch/Isaac1336853/1336722 将研究磁场中小体积氧化还原聚合物修饰电极的选择性激活，以在空间和时间上控制微流体。与在溶液中添加氧化还原物质或根本不添加氧化还原物质不同，这种新形式的磁流体动力学 (MHD) 克服了阻碍 MHD 在芯片实验室 ​​(LOAC) 设备中使用的问题。它允许更高的电流和更低的电压，因此具有更高的 MHD 力和更快的速度，而不会形成气泡或腐蚀，响应时间更快，并且与探测器和样品兼容。与其他微型泵相比，MHD 具有更大的多功能性，因为可以对流量进行编程，而无需重新设计设备的通道。大学化学与生物化学研究人员之间的跨学科、预先存在的合作。阿肯色州大学和密苏里大学机械与航空航天工程专业。科学技术部将进行这项研究。智力成果：限制在电极上聚合物膜中的化学物质的还原/氧化在溶液中产生离子电流。当与磁场成直角时，产生的 MHD 力会导致流体在三维空间中流动。单独寻址的电极将被制造成所需的图案，聚合物薄膜将被聚合并通过电化学表征，电极将被磁场中的电流和电压激活，并且流量将通过微珠在溶液中的运动来监测。目标是 (1) 为电极上的氧化还原聚合物薄膜建立大库仑容量、快速响应和等效电路模型，(2) 控制和最大化流速、调整分布、切换方向并使用同心驱动相邻逆流垂直于磁场的氧化还原聚合物修饰电极的圆盘环配置，(3) 通过对氧化还原聚合物薄膜再充电来维持流体流动，以及 (4) 使用模拟来获得离子电流密度、MHD 力密度和流体速度作为时间的函数，与实验进行比较，并评估超出实验限制的参数，以更好地设计氧化还原 MHD 微流体装置。更广泛的影响：目标是以可编程方式控制微流体，对感兴趣的产品产生深远的影响向公众提供的产品，例如用于医疗、环境和家庭用途的手持式独立化学分析装置。该项目的跨学科性质加强了对参与研究的学生的培训。完成的软件模块将免费提供给科学界进行测试和进一步评估。 新学校的科学、数学和语言艺术教师与阿尔伯塔大学和密苏里科技大学的导师之间的外展合作将以 MHD 作为起点，激发中学生关于力和能量主题的病毒式学习。学生将与教师和导师合作执行自主项目，使用自己的词汇和观点通过视频传达结果，这些视频是他们编写、编辑、制作的，并将其发布在互联网上供公众观看和评论。这种方法有望弥合大学研究和中学教育之间的差距，同时加强 STEM 教育和教育者发展，提高公众科学素养和公众对科学技术的参与。