MRI: Acquisition of PS-3 Automated Peptide Synthesizer to Enhance Research and Training at Texas A&M International University

MRI：购买 PS-3 自动肽合成仪以加强德克萨斯 A 的研究和培训

• 批准号: 1335988
• 负责人: Alfred Addo-Mensah
• 金额: $ 4.16万
• 依托单位: Texas A&M International University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1335988&HistoricalAwards=false
• 关键词: MRI; Acquisition; PS; Automated; Peptide

1335988GuptaThis MRI project proposal requests funds for an automated PS3 peptide synthesizer system tofacilitate the expansion of a peptide chemistry laboratory at Texas A&M International University(TAMIU), a Hispanic serving institution in South Texas. To foster the continued expansionof research at TAMIU and to better provide educational/research opportunities for their students,this proposal requests funding for equipment that will: 1) contribute to the limited understandingof the mechanism by which cell penetrating peptides (CPPs) translocate cell membranes; 2)increase knowledge of which key spider silk peptides are associated with specific mechanicalproperties; 3) elucidate the mechanisms of carbohydrates receptors responsible for malignantbehavior of cancerous cells 4) provide training and access a research methodology to a largenumber of predominantly Hispanic students, who are historically underrepresented in math andscience professions; 5) augment the education experience of several existing biology coursesand enable the creation of an additional elective chemistry course on polymers; 6) fosterintramural and extramural collaborations, and 7) increase TAMIU?s competitiveness for extramuralresearch funding and publications.

1335988 GUPTATHIS MRI项目建议要求为自动化的PS3 PS3肽合成器系统提供资金。为了促进TAMIU的持续扩展研究，并更好地为学生提供教育/研究机会，该提案要求为设备提供资金：1）有助于有限的理解细胞穿透性肽（CPPS）转运细胞膜的机制； 2）增加知识的知识与特定的机械杂质有关； 3）阐明负责癌细胞恶性肿瘤的碳水化合物受体的机制4）提供培训并访问主要是西班牙裔学生的大量研究方法，这些学生历来在数学和科学专业领域都有缺乏代表性； 5）增强几种现有生物学课程的教育经验，并使创建有关聚合物的额外的选修课课程； 6）养育和壁外合作，以及7）提高Tamiu的竞争能力，以实现校外研究资金和出版物的竞争力。