Workshop: International Meeting on Protein Folding and Dynamics; to be held October 15-17, 2012 in Bangalore, India

研讨会：蛋白质折叠和动力学国际会议；

• 批准号: 1241302
• 负责人: Devarajan Thirumalai
• 金额: $ 2.78万
• 依托单位: University of Maryland, College Park
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-15 至 2013-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1241302&HistoricalAwards=false
• 关键词: Workshop; International; Meeting; Protein; Folding

This award is in support of a two-day meeting entitled "International Meeting on Protein Folding and Dynamics" to be held at the International Center for Biological Sciences (NCBS) in Bangalore, India, on October 15-17, 2012. The purpose of the meeting is to bring together scientists from the USA, Europe, and Asia to discuss recent advances and future research in the area of protein folding. In addition, the conference will serve as an inaugural forum for introducing some of the activities in the newly initiated institutions (NCBS, Technical University of Munich, and the University of Maryland) into the Physics of Living Systems (POLS) network. This conference, therefore, takes on the importance of formally informing the students in NCBS to the activities and benefits of the POLS network. Among the invited speakers several are also part of the Network nodes.About twenty researchers representing a broad range of expertise and vision will be assembled with the purpose of assessing the outstanding problems in folding of proteins, and how these are related to function at larger scales. This workshop will convene about 20 speakers that represent all areas of protein folding as well as areas related to the assembly of proteins into larger complexes and higher order organized structures. One of the great challenges in biology is to integrate knowledge and capabilities at the individual subunit level with the ability to describe how these interact to affect function at the cellular level. The major aim of the meeting is to identify major issues that must be addressed in theory, simulations, and experiments in the next decade so that the roles which proteins play to carry out the myriad functions at the cellular level, in concert and in isolation, can be assessed and predicted. The meeting will cover the major unsolved problems in the area of protein folding, identify common themes, and chart a course for how to integrate the behavior of individual subunits to describe phenomena at the systems level. Broader impacts: This workshop is a unique way to assemble some of the leading scientists in the world to discuss topics that are never discussed in such depth at traditional meetings. Second, the exchange of ideas will be crucial in identifying new areas of research, which have to be tackled in the immediate future as we develop a language and framework for the next phase of quantitative research in biology. A broad spectrum of scientists with backgrounds in physics, chemistry and biology will be brought together to define the issues that have to be tackled and to identify the approaches that are needed.

该奖项是为了支持为期两天的会议，题为“国际蛋白质折叠和动态会议”将于2012年10月15日至17日在印度班加罗尔的国际生物科学中心（NCBS）举行。该会议的目的是将美国，欧洲和亚洲的科学家汇集在一起​​，以讨论蛋白质折叠领域的最新进步和未来研究。此外，该会议将作为首届论坛，以在新启动的机构（NCBS，慕尼黑技术大学和马里兰大学）中介绍一些活动中的某些活动，以介绍生活系统物理（POLS）网络。因此，这次会议将正式告知NCB的学生参加POLS网络的活动和好处的重要性。 在受邀的演讲者中，几个也是网络节点的一部分。将组装代表广泛的专业知识和视野的二十位研究人员，目的是评估蛋白质折叠的出色问题，以及这些与在较大尺度上的功能如何相关。该研讨会将召集大约20位扬声器，代表蛋白质折叠的所有区域以及与蛋白质组装成较大络合物和高阶组织结构有关的区域。生物学的巨大挑战之一是将各个亚基水平的知识和能力与描述这些相互作用以在细胞级别影响功能的能力相结合。 会议的主要目的是确定未来十年中必须解决的主要问题，以便可以评估和预测蛋白质在蜂窝级和孤立的蜂窝级上发挥众多功能的作用。这次会议将涵盖蛋白质折叠领域的主要未解决问题，确定常见主题，并为如何整合单个亚基的行为以描述系统级别的现象。更广泛的影响：这个研讨会是组装世界上一些主要科学家的独特方式，讨论在传统会议上从未在如此深入讨论的主题。 其次，思想的交流对于确定新的研究领域至关重要，这在我们为下一个生物学定量研究的下一阶段的语言和框架中时必须在不久的将来解决。具有物理，化学和生物学背景背景的大量科学家将被汇集在一起​​，以定义必须解决的问题并确定所需的方法。