Conference: FASEB Summer Research Conference on Mitosis: Spindle Assembly and Function conference being held August 5-10, 2012 in Steamboat Springs, Colorado.

会议：FASEB 有丝分裂夏季研究会议：纺锤体组装和功能会议将于 2012 年 8 月 5 日至 10 日在科罗拉多州斯廷博特斯普林斯举行。

• 批准号: 1240213
• 负责人: Claire Walczak
• 金额: $ 0.75万
• 依托单位: Federation of Amer Societies For Exper Biology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2013-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1240213&HistoricalAwards=false
• 关键词: Conference; FASEB; Summer; Research; Mitosis

Objectives: Cell division (mitosis) is the culmination of the cell cycle, and even seemingly minute deficiencies in the molecular mechanisms that control mitosis profoundly affect the fate of the daughter cells and ultimately, the fate of the entire organism. As such, elucidating the fundamental mechanisms of cell division has been in the focus of cell biology ever since this dynamic and complex process was revealed by early microscopy. A vast number of scientists investigate various aspects of the mitotic apparatus assembly and function. In fact, the field of mitosis amalgamates molecular cell biology, biochemistry, biophysics, computational biology, and functional genomics. To foster exchange of the information and ideas, as well as to encourage new interdisciplinary collaborations funds are requested to provide NSF travel awards for young scientists (graduate students, post-docs, and junior faculty) to attend the FASEB sponsored meeting on Mitosis: Spindle Assembly and Function.Intellectual Merit: This international meeting, organized by professors Claire Walczak of Indiana University (Bloomington, Indiana, USA) and Erich Nigg of Biozentrum, University of Basel (Basel, Switzerland), will bring together approximately 175 researchers from the various subdisciplines within the field of mitosis. The overall aim of the meeting is to encourage direct exchange of ideas and experimental data among scientists who study diverse aspects of mitosis. The meeting will feature a keynote address by the eminent scientist Dr. Conly Rieder of the Wadsworth Center (Albany, NY). His lecture will focus on conceptual developments in the understanding of cell division, and it will put recently-unveiled molecular mechanisms in the context of live-cell microscopy observations made over the course of several decades. Podium presentations will feature invited internationally-renowned experts, as well as younger scientists (graduate students, post-docs, and junior faculty) whose work will be selected from the submitted abstracts. Nine platform sections covering all major aspects of mitosis will be held: 1. Mitotic spindle assembly; 2. Quantitative approaches to mitosis; 3. Centrosome structure and function; 4. Kinetochore assembly and function; 5. Chromosome structure and function; 6. Mitosis career symposium; 7. Cytokinesis and mitotic exit; 8. Chromosome segregation and aneuploidy; 9. Mitosis in Development. Of special note is the Mitosis Career Symposium in which three senior leaders in the field (Professors Dick McIntosh, MaryAnn Jordan, and Ted Salmon) will provide an overview of their many contributions to this field. In addition, the session on quantitative approaches to mitosis represents the newest multidisciplinary science that is critical to the future of this field, and the session on mitosis in development is aimed to integrate the cell biology with mitosis in the broader context of the organism. To complement the platform sessions, time will be allocated for three poster sessions, each 2 hours long. The remainder of the afternoons will be orchestrated for informal scientific exchanges to promote cross-disciplinary interactions and to nurture the initiation of new collaborations.Broader Impacts: A unique feature of the meeting is that it will focus on disseminating new cutting-edge information in a didactic and expertly assimilated form, which is essential in the rapidly changing scientific landscape of research in mitosis. Due to enormously vast and diverse professional literature it has become difficult, particularly for younger scientists who only recently entered the field, to view individual discoveries in a common perspective. In addition, because of the small size and informal nature of the meeting, this venue provides a unique opportunity for young scientists to interact with world-renowned experts in the field to gain their insight and perspective on their research. Graduate students, post-doctoral fellows, and junior faculty will all be considered for platform presentations to feature their work, and all attendees are expected to present research in platform or poster sessions to ensure that everyone actively participates in the meeting. The information gathered from this meeting will be used to advance both the research and educational goals of the meeting participants by broadly disseminating the latest information to participants, who are actively involved in graduate and undergraduate training and education at institutions throughout the world.

目的：细胞分裂（有丝分裂）是细胞周期的结晶，甚至在控制有丝分裂的分子机制中似乎是微小的缺陷，这些分子机制会深刻影响子细胞的命运，最终影响整个生物体的命运。因此，自从早期显微镜揭示了这种动态和复杂的过程以来，阐明细胞分裂的基本机制一直是细胞生物学的重点。许多科学家研究了有丝分裂设备组装和功能的各个方面。实际上，有丝分裂的领域是合并分子细胞生物学，生物化学，生物物理学，计算生物学和功能基因组学。要求促进信息和想法以及鼓励新的跨学科合作资金，要求为年轻科学家（研究生，毕业后和初级教职员工）提供NSF旅行奖，以参加有遇到的faseb赞助会议：Spindle：Spindle：集会和功能。智能优点：由印第安纳大学（美国印第安纳州布卢明顿）教授克莱尔·沃尔卡克（Claire Walczak）和Biozentrum的Erich Nigg组织，巴塞尔大学巴塞尔大学（瑞士巴塞尔）（瑞士巴塞尔大学）组织的这次国际会议，将从有丝分裂领域内的子学科。会议的总体目的是鼓励研究有丝分裂的各个方面的科学家之间直接交流思想和实验数据。会议将由沃兹沃思中心（纽约州奥尔巴尼）的著名科学家科利·里德尔博士的主题演讲。他的演讲将集中在对细胞分裂理解的概念发展上，并将在几十年的实时细胞显微镜观察中将最近解开的分子机制提出。讲台的演讲将以受邀国际知名的专家以及年轻的科学家（研究生，毕业后和初级教师）为特色，他们的工作将从提交的摘要中选择。将举行涵盖有丝分裂所有主要方面的九个平台部分：1。有丝分裂纺锤体组件； 2。有丝分裂的定量方法； 3。中心体的结构和功能； 4。动力学组装和功能； 5。染色体结构和功能； 6。有丝分裂职业研讨会； 7。细胞因子和有丝分裂出口； 8。染色体分离和非整倍性； 9。发育有丝分裂。特别值得注意的是有丝分裂职业研讨会，该研讨会在该领域的三名高级领导人（教授迪克·麦金托什，玛丽安·乔丹和泰德·鲑鱼）将概述他们对这一领域的许多贡献。此外，有关有丝分裂定量方法的会议代表了对该领域未来至关重要的最新多学科科学，并且有关开发中的有丝分裂的旨在将细胞生物学与有丝分裂纳入更广泛的生物体环境。为了补充平台会议，将分配三个海报会议，每2个小时。其余的下午将精心策划进行非正式的科学交流，以促进跨学科的互动并培养新合作的启动。Broader的影响：会议的独特功能是，它将集中于在某种程度上传播新的切割信息是有丝分裂研究的迅速变化的科学景观至关重要的。由于非常广泛而多样的专业文学，这变得困难，尤其是对于直到最近才进入该领域的年轻科学家而言，以共同的观点查看个人发现。此外，由于会议的规模和非正式性质，该场所为年轻科学家提供了一个独特的机会，使年轻的科学家与该领域的世界知名专家进行互动，以了解他们的研究。研究生，博士后研究员和初级教职员工都将被考虑以进行平台演讲以展示其工作，并且所有与会者均应在平台或海报会议上进行研究，以确保每个人都积极参加会议。从这次会议中收集的信息将用于通过向参与者广泛传播最新信息来推进会议参与者的研究和教育目标，他们积极参与了全世界机构的研究生和本科培训和教育。