REU Site: Engineering Tools for Decision Support in Systems Medicine

REU 网站：系统医学决策支持工程工具

• 批准号: 1156899
• 负责人: Robert Parker
• 金额: $ 35.77万
• 依托单位: University of Pittsburgh
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-01 至 2017-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1156899&HistoricalAwards=false
• 关键词: REU; Site; Engineering; Tools; Decision

Intellectual MeritThe primary objective of this new three-year REU site program at the University of Pittsburgh is to expose 9 undergraduate students per year to research in the emerging field of systems medicine. Systems medicine problems are characterized by complex interacting systems requiring multidisciplinary knowledge to formulate and solve. The intellectual merit of this REU proposal derives from the emergence of this field and the need for experts with the knowledge and motivation to address constrained real-world problems where mathematical models can provide hypothesis-generating and in validating predictions. Furthermore, systems medicine is underserved by existing REU sites, in comparison to other areas of biomedical research, and this site would expand the existing REU portfolio while educating students who could serve as the next generation of leaders in the field. The necessity of coupling modeling and systems analysis approaches to experimental data; thereby yielding a predictive model upon validation is a prerequisite to solving clinically-relevant systems medicine problems. Through a series of mentored research and teaching experiences, REU students will take the first step on the path to becoming the next generation of experts in the field of systems medicine.Broader ImpactsThe PI will actively recruit underrepresented undergraduates to participate in interdisciplinary research and to advance the abilities of all students in the program with respect to communication, teamwork, and professional skills. Through existing relationships, and the development of new ones with minority, female, or primarily undergraduate institutions, the program will provide a pathway to graduate education for populations that are traditionally underrepresented at the engineering (and STEM) post-graduate level by fostering the ability to independently and collaboratively investigate systems medicine research problems. One path of dissemination is to design simulations for use in K-12 education; through partnering with the CTSI "Mobile Lab" to bring computational experiments to K-12 students in an effort to stimulate the desire of these students to pursue STEM subjects at the baccalaureate level.

智力优势匹兹堡大学这个新的为期三年的 REU 站点项目的主要目标是每年让 9 名本科生接触新兴系统医学领域的研究。系统医学问题的特点是复杂的相互作用系统，需要多学科知识来制定和解决。 REU 提案的智力价值源于该领域的出现，以及对具有知识和动力的专家的需求，以解决受限的现实世界问题，其中数学模型可以提供假设生成和验证预测。此外，与生物医学研究的其他领域相比，现有 REU 站点对系统医学的服务不足，该站点将扩大现有 REU 的投资组合，同时教育可以成为该领域下一代领导者的学生。将建模和系统分析方法与实验数据耦合的必要性；因此，在验证后产生预测模型是解决临床相关系统医学问题的先决条件。通过一系列受指导的研究和教学经验，REU 学生将迈出成为系统医学领域下一代专家的第一步。 更广泛的影响 PI 将积极招募代表性不足的本科生参与跨学科研究并推进该项目中所有学生在沟通、团队合作和专业技能方面的能力。通过现有的关系以及与少数族裔、女性或主要本科院校建立的新关系，该计划将通过培养能力，为传统上在工程（和 STEM）研究生水平上代表性不足的人群提供研究生教育的途径。独立和协作研究系统医学研究问题。传播途径之一是设计用于 K-12 教育的模拟；通过与 CTSI“移动实验室”合作，为 K-12 学生带来计算实验，努力激发这些学生攻读学士学位水平的 STEM 科目的愿望。