Collaborative Research: ABI Development: Building A Community Resource for Neuroscientists

合作研究：ABI 开发：为神经科学家建立社区资源

• 批准号: 1146949
• 负责人: Amitava Majumdar
• 金额: $ 70.66万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1146949&HistoricalAwards=false
• 关键词: Collaborative; Research; ABI; Development; Building

The University of California-San Diego and Yale University are awarded collaborative grants to develop a Neuroscience Gateway (NSG) that will facilitate access and use of high performance computing (HPC) resources by neuroscientists. Computational modeling of cells and networks has become an essential part of neuroscience research, and investigators are using models to address problems of ever increasing complexity, e.g. large scale network models and optimization or exploration of high dimensional parameter spaces. The NSG will catalyze such research by lowering or eliminating the administrative and technical barriers that currently make it difficult for investigators to use HPC resources. It will offer computer time to neuroscience users through an administratively and technologically streamlined process with a simple web portal-based environment for uploading models, specifying HPC job parameters, querying running job status and receiving job completion notices, and retrieving and storing output data. The URL of the NSG portal is http://www.nsgportal.org. It will also provide a community forum for neuroscientists to collaborate and share data. The NSG architecture will transparently distribute user jobs to appropriate HPC resources provided by NSF supercomputer centers. The NSG team will collaborate with developers of neural simulation software to optimally install, test, and benchmark these applications on HPC machines, and allow developers to test new versions before release. This project will have a transformative impact by enabling access by members of the computational neuroscience community to HPC resources for research and instruction involving compute-intensive simulations (typically large neural networks). Many of these investigators and students would otherwise find it very difficult, if not impossible, to implement and study models that press or exceed the storage and speed capabilities that are under their direct control. Computational modeling offers opportunities for students and researchers at institutions with limited resources for wet lab or experimental infrastructure to participate in leading edge science. Projects such as this, which facilitate access to HPC resources, democratize participation in science by mitigating the financial barriers to research infrastructure. The NSG will enable students and researchers, who lack access to HPC resources and are thus at a significant disadvantage compared to very few who have it, by removing the barriers for progress for many including historically underrepresented groups. The PIs of this project will target the promotion of the NSG to underrepresented minority scientists and minority serving institutions through active participation in summer training academies and a network of previously mentored female and minority students, some now employed at minority serving institutions.

加利福尼亚大学迭戈大学和耶鲁大学获得了合作赠款，以开发神经科学网关（NSG），这些神经科学将促进神经科学家的访问和使用。细胞和网络的计算建模已成为神经科学研究的重要组成部分，研究人员正在使用模型来解决越来越复杂的问题，例如大型网络模型以及高维参数空间的优化或探索。 NSG将通过降低或消除目前使研究人员难以使用HPC资源的行政和技术障碍来促进此类研究。它将通过管理和技术精简的流程为使用简单的基于Web门户网站的环境，用于上传模型，指定HPC作业参数，查询运行工作状态并接收工作完成通知以及检索和存储输出数据。 NSG门户网站的URL是http://www.nsgportal.org。它还将为神经科学家提供一个社区论坛，以协作和共享数据。 NSG体系结构将透明地将用户作业分配给NSF超级计算机中心提供的适当的HPC资源。 NSG团队将与神经模拟软件的开发人员合作，以最佳的安装，测试和基准在HPC机器上进行这些应用程序，并允许开发人员在发布前测试新版本。该项目将通过使计算神经科学社区的成员访问HPC资源，以进行涉及计算密集型模拟（通常是大型神经网络）的研究和指导，从而产生变革性的影响。这些调查人员和学生中的许多人否则会发现，即使不是不可能，也很难实施和研究超越其直接控制的存储和速度功能的模型。计算建模为机构的学生和研究人员提供了机会，该机构的资源有限，用于湿实验室或实验基础设施，以参与领先的科学。这样的项目通过减轻研究基础设施的财务障碍来促进HPC资源的访问，使参与科学的参与民主化。 NSG将通过消除包括历史上代表性不足的群体在内的许多人的进步障碍，使他们无法获得HPC资源的学生和研究人员，因此与少数拥有该资源的人相比处于严重的劣势。该项目的PI将以积极参与夏季培训学院的积极参与以及以前受过指导的女性和少数族裔学生的网络来促进NSG晋升为代表性不足的少数群体科学家和少数民族服务机构，其中一些人现在在少数民族服务机构工作。