DISSERTATION RESEARCH: The genetics of female preference in Drosophila subquinaria

论文研究：果蝇雌性偏好的遗传学

• 批准号: 1110462
• 负责人: Kelly Dyer
• 金额: $ 1.5万
• 依托单位: University of Georgia Research Foundation Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-15 至 2014-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1110462&HistoricalAwards=false
• 关键词: DISSERTATION; RESEARCH; genetics; female; preference

How do new species arise? A central goal of evolutionary biology is to understand how new species form and the processes that maintain boundaries between species. This research will investigate whether selection to strengthen reproductive barriers between species may, as a consequence, also initiate reproductive isolation within species. The specific goal of this project is to dissect the genetic basis of female mate preference in the fly Drosophila subquinaria, a species where some females display increased behavioral discrimination both against males of a closely related species as well as against certain males of their own species. Using crossing experiments and genome sequencing technologies, the experiments will ask whether the same genetic regions confer increased mate discrimination within and between species. In addition to advancing our understanding of the genetic basis of behavioral isolation and speciation, this research will also involve the development of genetic resources for the quinaria group of Drosophila, a group that has undergone a recent radiation and has considerable potential as model system for evolutionary, ecological, and behavior genetic studies. This funding will also provide research training in the areas of behavior, genetics, and bioinformatics for a female graduate student as well as for undergraduate and high school students from diverse backgrounds.

新物种如何出现？ 进化生物学的一个核心目标是了解新物种形成和维持物种之间边界的过程如何。这项研究将调查加强物种之间生殖屏障的选择是否可能也可能引发物种内的生殖隔离。 该项目的具体目标是剖析果蝇果蝇亚果中女性伴侣偏好的遗传基础，在这种物种中，某些女性对紧密相关物种的男性以及对自己的某些雄性物种的男性表现出了增加的行为歧视。 使用交叉实验和基因组测序技术，实验将询问相同的遗传区域是否会增加物种内部和物种之间的伴侣歧视。 除了促进我们对行为隔离和物种形成的遗传基础的理解之外，这项研究还将涉及果蝇奎纳里亚群的遗传资源的发展，果蝇的奎纳里亚群是最近经历了近期辐射的群体，并且具有相当大的潜力作为进化，生态和行为遗传研究的模型系统。 这项资金还将为女性研究生以及来自不同背景的本科生和高中生提供行为，遗传学和生物信息学领域的研究培训。