CPS: Large: Assuring the Safety, Security and Reliability of Medical Device Cyber Physical Systems

CPS：大型：确保医疗器械信息物理系统的安全性、保密性和可靠性

• 批准号: 1035715
• 负责人: Insup Lee
• 金额: $ 495万
• 依托单位: University of Pennsylvania
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-10-01 至 2017-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1035715&HistoricalAwards=false
• 关键词: CPS; Large; Assuring; Safety; Security

The objective of this research is to establish a new development paradigm that enables the effective design, implementation, and certification of medical device cyber-physical systems. The approach is to pursue the following research directions: 1) to support medical device interconnectivity and interoperability with network-enabled control; 2) to apply coordination between medical devices to support emerging clinical scenarios; 3) to ?close the loop? and enable feedback about the condition of the patient to the devices delivering therapy; and 4) to assure safety and effectiveness of interoperating medical devices.The intellectual merits of the project are 1) foundations for rigorous development, which include formalization of clinical scenarios, operational procedures, and architectures of medical device systems, as well as patient and caregiver modeling; 2) high-confidence software development for medical device systems that includes the safe and effective composition of clinical scenarios and devices into a dynamically assembled system; 3) validation and certification of medical device cyber-physical systems; and 4) education of the next-generation of medical device system developers who must be literate in both computational and physical aspects of devices.The broader impacts of the project will be achieved in three ways. Novel design methods and certification techniques will significantly improve patient safety. The introduction of closed-loop scenarios into clinical practice will reduce the burden that caregivers are currently facing and will have the potential of reducing the overall costs of health care. Finally, the educational efforts and outreach activities will increase awareness of careers in the area of medical device systems and help attract women and under-represented minorities to the field.

这项研究的目的是建立一个新的开发范式，以实现医疗设备网络物理系统的有效设计，实施和认证。 方法是追求以下研究方向：1）支持医疗设备互连性和与网络启用控制的互操作性； 2）在医疗设备之间应用协调以支持新兴的临床情况； 3）关闭循环？并能够就患者的状况进行提供治疗的设备的反馈； 4）确保互操作医疗设备的安全性和有效性。 2）医疗设备系统的高信心软件开发，其中包括将临床场景和设备安全有效组成到动态组装系统中； 3）医疗设备网络物理系统的验证和认证； 4）对必须在设备的计算和物理方面识字的医疗设备系统开发人员的下一代教育。项目的更广泛影响将以三种方式实现。新颖的设计方法和认证技术将显着提高患者的安全性。 将闭环情景引入临床实践将减轻护理人员目前面临的负担，并有可能降低医疗保健的整体成本。 最后，教育工作和外展活动将提高医疗设备系统领域的职业意识，并帮助吸引妇女和代表性不足的少数群体进入该领域。