2010 Protein Folding Dynamics Gordon Research Conference and Seminar in Ventura, CA from January 9-15, 2010

2010 年蛋白质折叠动力学 Gordon 研究会议和研讨会于 2010 年 1 月 9 日至 15 日在加利福尼亚州文图拉举行

• 批准号: 0949243
• 负责人: Susan Marqusee
• 金额: $ 1.8万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0949243&HistoricalAwards=false
• 关键词: 2010; Protein; Folding; Dynamics; Gordon

The 5th Gordon Research Conference on Protein Folding Dynamics and the accompanying Graduate Research Seminar, which is a workshop for graduate students and post docs addressing the methods and models of protein folding will take place at the Ventura Beach Marriott,Ventura, California from January 9-10 (GRS) and January 10-15 (GRC), 2010. Funding from the NSF will allow a broad participation from both young and established scientists working in this field. Protein folding is a multidisciplinary area of research addressing fundamental problems in biology. Consequently, few other fields see such a successful blend of physical and biological sciences. Progressively, more studies that bring together experiment and theory are being published, and this combination is advancing our fundamental quantitative understanding of the information encoded within protein sequences. Technological and theoretical advances have altered our view of the protein folding and dynamics. Fast events can be observed experimentally on timescales that approach those accessible by all-atom molecular dynamics simulations. New,sophisticated models of proteins allow ensemble kinetics to be sampled and compared to experiment.The Gordon Research Conference in Protein Folding Dynamics, is a relatively new conference,first set up in 2002, aimed specifically to bring experiment and theory together to explore advances in the field and to serve as a forum to discuss fundamental problems from polypeptide energetics and dynamics; to chaperone assisted folding and the relationship between protein misfolding and disease.Broader Impacts: As the field matures and development in the physical sciences are being applied to important problems in protein dynamics and energetics, it becomes even more important to provide this venue to foster this communication and training at this interface between theory and experiment. The GRC fosters an environment that attracts the brightest and the most interactive members of the community. The ideas and hypotheses developed at this conference will continue to advance the field of protein folding dynamics as well as larger community interested in understanding the information encoded in protein sequences, fields as diverse as biomaterials to human genetics.The Graduate Research Seminar in Protein Folding Dynamics is a meeting being organized as a satellite to the GRC in Protein Folding Dynamics. This workshop serves as a venue for graduate students and postdoctoral scientists to i) develop background on current techniques, theories and models in preparation for the GRC in Protein Folding Dynamics, ii) share their knowledge of protein folding methodologies and techniques and iii) meet each other and discuss their own research. The involvement and inclusion of young and developing scientists represents a key objective in the vision of the conference to provide this vibrant multi-disciplinary research area with scientists who are broadly based in both experimental protein folding methodologies and the models and theories that provide a basis for the interpretation of experiment in this field.

第五届戈登蛋白质折叠动力学研究会议和随附的研究生研究研讨会，该研讨会是研究生的研讨会，并发布了有关蛋白质折叠方法和模型的文档的讲习班，将在1月9-10日（GRS）和2010年1月10日（grc）的Ventura海滩万豪酒店举行。 场地。蛋白质折叠是解决生物学基本问题的研究的一个多学科领域。因此，很少有其他领域看到了物理和生物学科学的成功融合。逐步发表了更多的研究，将实验和理论汇集在一起​​，这种组合正在推进我们对蛋白质序列中编码的信息的基本定量理解。技术和理论进步改变了我们对蛋白质折叠和动态的看法。可以在接近通过全原子分子动力学模拟访问的时间表上实验观察到快速事件。蛋白质的新型，复杂的模型允许对集合动力学进行采样并与实验进行比较。Gordon蛋白质折叠动力学研究会议是一个相对较新的会议，首次成立于2002年，旨在将实验和理论聚集在一起，以探索领域的进步，并旨在讨论来自多肽和动力学的基本问题的田野和论坛，以探索AS论坛。伴侣的辅助折叠以及蛋白质错误折叠和疾病之间的关系。BRODER的影响：随着物理科学的现场成熟和发展被应用于蛋白质动力学和能量学的重要问题时，为在理论和实验之间提供这种沟通和训练的场所变得更加重要。 GRC促进了一个吸引社区中最聪明和最互动成员的环境。在这次会议上提出的思想和假设将继续推进蛋白质折叠动力学领域，以及有兴趣了解蛋白质序列中编码的信息，与人类遗传学的生物材料一样多样化的领域。该研讨会是研究生和博士后科学家的场所。年轻人和发展科学家的参与和包容是会议愿景中的一个关键目标，即与科学家提供这个充满活力的多学科研究领域，这些科学家在实验蛋白质折叠方法中广泛基于实验蛋白质折叠方法和模型和理论，这些模型和理论为这一领域的实验解释提供了基础。