Collaborative Research: Acquisition of a 400 MHz NMR at the University of Southern California

合作研究：在南加州大学购买 400 MHz NMR

• 批准号: 0840366
• 负责人: Mark Thompson
• 金额: $ 46.92万
• 依托单位: University of Southern California
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0840366&HistoricalAwards=false
• 关键词: Collaborative; Research; Acquisition; 400; MHz

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With support from the Chemistry Research Instrumentation and Facilities: Multiuser program (CRIF:MU), the Departments of Chemistry at the University of Southern California (USC) and California State University - Fullerton (CSUF) will collaborate on the acquisition and remote control cyber enabling of a 400 MHz nuclear magnetic resonance (NMR) spectrometer to be housed at USC. It will be employed in a wide variety of research projects, supporting structural, reaction, and analytical studies such as 1) new synthetic routes to inorganic nanocrystals; 2) the development of new synthetic methods in organic and organometallic chemistry; 3) studies of biologically important organophosphorus compounds; 4) new synthetic methods and synthesis of bioactive molecules; and 5) the design of novel RNA binding peptides. Multinuclear NMR spectroscopy is a key analysis and characterization tool in chemistry today. The spectra enable researchers to track the progress of chemical reactions, identify unknown substances and provide information on the atomic arrangement and structures in species ranging from small molecules to large proteins by detecting transitions between energy levels arising from the nuclear spin properties of atoms. This instrument will support the education of future scientists at levels from undergraduate, to graduate student, to postdoctoral research associate. It will be used in lab courses for both chemistry and biochemistry students at USC and CSUF. Cyber infrastructure will be developed for both the remote control of the autosampler enabled instrument, as well as remote access for data collection/analysis from the instrument with a web based system. A practical NMR methods course will be developed jointly at USC and CSUF to train students in the use of the NMR spectrometer.

该奖项由 2009 年美国复苏和再投资法案（公法 111-5）资助。在化学研究仪器和设施：多用户计划 (CRIF:MU) 的支持下，南加州大学化学系 ( USC）和加州州立大学富勒顿分校 (CSUF) 将合作对位于 USC 的 400 MHz 核磁共振 (NMR) 波谱仪进行采集和远程控制网络支持。 它将用于各种研究项目，支持结构、反应和分析研究，例如1）无机纳米晶体的新合成路线； 2）有机和有机金属化学新合成方法的发展； 3）生物学上重要的有机磷化合物的研究； 4）新的合成方法和生物活性分子的合成； 5）新型RNA结合肽的设计。多核核磁共振波谱是当今化学中的关键分析和表征工具。这些光谱使研究人员能够跟踪化学反应的进展，识别未知物质，并通过检测原子核自旋特性引起的能级之间的转变，提供从小分子到大蛋白质的原子排列和结构信息。 该仪器将支持未来科学家从本科生到研究生再到博士后研究员的教育。 它将用于南加州大学和 CSUF 化学和生物化学学生的实验课程。 将开发网络基础设施，用于远程控制自动进样器启用的仪器，以及通过基于网络的系统从仪器远程访问数据收集/分析。 南加州大学和 CSUF 将联合开发实用的核磁共振方法课程，以培训学生使用核磁共振波谱仪。