SGER: Microarray Analysis of Caste Ontogeny in a Social Insect

SGER：社会性昆虫种姓个体发育的微阵列分析

• 批准号: 0819807
• 负责人: James Hunt
• 金额: --
• 依托单位: North Carolina State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0819807&HistoricalAwards=false
• 关键词: SGER; Microarray; Analysis; Caste; Ontogeny

James Howell HuntIOS-0819807SGER: Microarray analysis of caste ontogeny in a social insectThe interplay of environment and development shapes individuals and animal societies. The starting point, however, is in the genes. New tools of molecular biology are giving new insights into roles played by each factor: genes, environment, and development; and how they relate to one another in shaping the natural world. Social insects, including pest ants and termites, pose special challenges to understanding. Thus, it is both timely and important to take advantage of new molecular biology technologies to identify specific genes that are affected by the environment as they regulate the development of a social insect colony. A simple insect society is more suitable for experimental molecular biology than are large colonies of fire ants or termites. The objective of the research, therefore, is to employ a new molecular tool, a microarray of genes, to identify specific genes in a paper wasp species that are affected by the environment as they regulate the development of workers and reproductives in the wasp colony. An important broader impact of the research is that the results should be widely applicable to ants, bees, and termites, including economically important species such as pest ants and endangered pollinators such as bumble bees. As an additional broader impact, undergraduate students will be given training and experience in several levels of biological research (behavior, ecology, molecular biology), and these students will go on to advanced training and careers in conservation, ecology, or biomedicine. To learn the molecular basis of development in a colony of social insects can be the gateway to new and deeper understanding of the interplay of genes, environment, and development, and it can also give us new research tools for future investigations for both control and protection of some of the world's most ecologically important insects.

James Howell Huntios-0819807Sger：社会昆虫中种姓的微阵列分析环境与发展的相互作用塑造了个人和动物社会。但是，起点是基因。分子生物学的新工具正在为每个因素扮演的角色：基因，环境和发展提供了新的见解；以及它们如何在塑造自然世界中相互联系。包括害虫蚂蚁和白蚁在内的社会昆虫对理解构成了特殊的挑战。因此，利用新的分子生物学技术来识别受环境影响的特定基因，因为它们调节社会昆虫菌落的发展，这既及时也很重要。一个简单的昆虫社会更适合于实验性分子生物学，而不是大的火蚂蚁或白蚁菌落。因此，该研究的目的是采用一种新的分子工具，一种基因的微阵列来识别受环境影响的纸质黄蜂物种中的特定基因，因为它们调节了黄蜂群体中工人的发展和生殖。该研究的一个重要的广泛影响是，结果应广泛适用于蚂蚁，蜜蜂和白蚁，包括经济上重要的物种，例如害虫蚂蚁和濒临灭绝的传粉媒介，例如大黄蜂。作为额外的更广泛的影响，本科生将在几个级别的生物学研究（行为，生态学，分子生物学）中进行培训和经验，这些学生将继续从事保护，生态学或生物医学的高级培训和职业。要了解社会昆虫群落中发展的分子基础，这可能是对基因，环境和发育相互作用的新的，更深入的了解的门户，并且还可以为我们提供新的研究工具，以控制和保护世界上一些最重要的昆虫。