The evolution and origins of uncooperative rhizobia

不合作根瘤菌的进化和起源

• 批准号: 0816663
• 负责人: Joel Sachs
• 金额: $ 25万
• 依托单位: University of California-Riverside
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0816663&HistoricalAwards=false
• 关键词: evolution; origins; uncooperative; rhizobia

Infection by symbiotic bacteria is critical to plant and animal health. However, these beneficial infections are predicted to be evolutionarily unstable. Bacteria that help hosts can potentially evolve into parasites that exploit hosts. Alternatively, they might shift into novel life histories and abandon host interaction entirely. Both evolutionary pathways can be harmful to hosts, as uncooperative bacteria spread and take over beneficial populations. Here, the symbiotic bacteria (rhizobia) found on legume roots will be used to examine instability of beneficial bacterial infections. Field surveys, inoculation assays, experimental evolution studies and molecular analyses will (i) assess the frequency with which uncooperative rhizobia emerge in wild symbiont populations, (ii) investigate the reproductive success of uncooperative strains, and (iii) test hypotheses about the evolutionary forces that can shape uncooperative rhizobial strategies.Symbiotic bacteria are a key yet poorly understood facet of life. Humans and our food sources often depend upon bacterial cooperation for health, and research is needed to investigate the origins of harmful strains. This research will provide clues about how and why host-beneficial bacteria shift into harmful modes. It will provide training opportunities to students, and results will be incorporated into classroom activities.

共生细菌感染对植物和动物健康至关重要。但是，预计这些有益的感染在进化上是不稳定的。帮助宿主的细菌可能会演变成利用宿主的寄生虫。另外，它们可能会转移到新颖的生活史中，并完全放弃宿主的互动。随着不合作性细菌的扩散并接管有益种群，这两种进化途径可能对宿主有害。在这里，在豆类根上发现的共生细菌（根瘤菌）将用于检查有益细菌感染的不稳定性。现场监测，接种测定，实验进化研究和分子分析将（i）评估野生共生群人群中出现不合作性根瘤菌的频率，（ii）研究不合作菌株的生殖成功，以及（iii）对进化的较差力量的差异型较差的动力，可以使不合适的脑静脉降低晶状体的策略，以下是不合适的策略。生活。人类和我们的食物来源通常取决于细菌合作以进行健康，需要研究来研究有害菌株的起源。这项研究将提供有关宿主伴有细菌如何以及为什么转变为有害模式的线索。它将为学生提供培训机会，并将结果纳入课堂活动。