CAREER: Synthesis, Characterization, and Phase Behavior of Poly(vinyl ester) Block Copolymers

职业：聚（乙烯基酯）嵌段共聚物的合成、表征和相行为

• 批准号: 0748503
• 负责人: Mahesh Mahanthappa
• 金额: $ 47.5万
• 依托单位: University of Wisconsin-Madison
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-02-01 至 2014-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0748503&HistoricalAwards=false
• 关键词: CAREER; Synthesis; Characterization; Phase; Behavior

TECHNICAL SUMMARY The goal of this project is to develop complementary free radical polymerizatin techniques to prepare unkown classes of block copolymers derived from vinyl ester monomers and to study their phase behavior in the melt state and in dilute aqueous solutions. Melt phase behavior studies will exploit a complement of experimental methods including small-angle x-ray scattering, rheology, and electron microscopy (SEM and TME). Due to the bulk availability of binyl ester monomers, these block copolymers may enable the design of new soft materials having tunable rheological properties useful in commodity applications. The known biodegradability of some vinyl ester homopolymers also warrants invetigations into the potential biodegradability of these new block copolymers. These studies will elucidate relationships between polymer composition and architecture, morphologym and degradability for this new palette of monomers. The synthetic methods developed herein will be extended to enable the synthesis of well-defined, monodisperse poly(vinyl alcohol)-based amphiphilic block copolymers. As a consequence of the presence of strongly interacting hydroxyl groups in the hydrophilic corona block, these new polymeric surfactants are expected to exhibit different phase behaviors and rheological properties in dilute aqueous dispersions, as compared to those of other non-ionic surfactants. The strongly couple interplay of vinyl ester block copolymer synthesis and physical characterization in this research will shed light on the fundamental molecular parameters that underpin bulk materials properties. NON-TECHNICAL SUMMARY The major objective of this project is to explore the synthesis and properties of a new class of nanstructures plastics, which potentially will exhibit novel degradability and find use in both commodity and value-added applications. These studies will serve as the foundation for long-term efforts to develop biodegradable polymers as well as polymeric soaps that systematically modify the flow properties of fluids such as water. By virtue of their derivation from cheap chemical feedstocks, one anticipates that these materials may be economically produced n large scales for applications including drug delivery, degradable tissue scaffolds and other biomedical devices, stabalization of dispersions in personal care and pharmaceutical products, and surfactants for enhanced oil recovery that will help to increase overall yields. These research effots will be integrated into a wide spectrum of educational activites aimed at increasing scientific, social, and political awareness about the importance of commodity chemical innovations, with the aim of broadening participation of under-represented groups in science, technology, engineering, and mathematics (STEM) disciplines. Situated at the interface of chemistry, chemical engineering, and materials science, this research project will train both graduate and undergraduate students to tackle important challenges in polymer science. Research results will be integrated into undergraduate curricula through the development of experiments for a polymer lab course intended to foster interdisciplinary communication between STEM students. Additionally, curriculum materials for secondary and post-secondary educators highlighting the broader social and political impacts of commodity chemical innovations will be developed. These materials will serve as a prototype for inclusive curricula that employ interdisciplinary connections to cast scientific problems in captivating broader contexts, while highlighting past, present, and future research and development activities.

技术摘要该项目的目的是开发互补的自由基聚合物技术，以准备源自乙烯基酯单体的无型块共聚物类别，并研究其在熔体状态和稀释水溶液中的相位行为。 熔融相行为研究将利用包括小角度X射线散射，流变学和电子显微镜（SEM和TME）在内的实验方法的补充。 由于二酯单体的大量可用性，这些块共聚物可以设计具有可调性流变特性的新软材料，可用于商品应用。 某些乙烯基酯均聚物的已知生物降解性还需要开创性，以使这些新块共聚物的潜在生物降解性。 这些研究将阐明这种新单体调色板的聚合物组成与建筑，形态和降解性之间的关系。 本文开发的合成方法将扩展，以实现良好定义的基于单分散的聚（乙烯基醇）基于两亲性块共聚物的合成。 由于与其他非离子表面活性剂相比，这些新的聚合物表面活性剂在亲水性电晕块中存在强相互作用的羟基在稀水散剂中的相互作用和流变特性不同。 在这项研究中，乙烯基酯块共聚物合成和物理表征的强烈相互作用将阐明基于大量材料特性的基本分子参数。 非技术摘要该项目的主要目的是探索新的NANTRUCTURS塑料的综合和特性，该塑料可能会表现出新颖的降解性并在商品和增值应用中找到使用。 这些研究将是长期努力开发可生物降解聚合物以及聚合物肥皂的基础，从而系统地改变了流体（例如水）的流动特性。 由于它们从廉价的化学原料中衍生而来，人们预计，这些材料可能是经济上生产的，用于应用，包括药物输送，可降解的组织支架和其他生物医学设备，个人护理和药品中分散物的稳定以及表面活性剂的稳定，以及增强油回收率的表面活性剂，这将有助于提高整体收益率。 这些研究结果将集成到各种各样的教育活动中，旨在提高对商品化学创新重要性的科学，社会和政治意识，以扩大代表性不足的群体参与科学，技术，工程，工程和数学（STEM）学科的参与。 该研究项目位于化学，化学工程和材料科学的界面，将培训研究生和本科生，以应对聚合物科学的重要挑战。 通过开发旨在促进STEM学生之间跨学科交流的聚合物实验室课程的实验，将将研究结果纳入本科课程。 此外，将开发出二级和大专教育的课程材料，重点介绍商品化学创新的更广泛的社会和政治影响。 这些材料将作为包容性课程的原型，这些课程采用跨学科联系，以在吸引更广泛的环境中引起科学问题，同时强调过去，现在和未来的研究和发展活动。