EXP-SA: Receptor-Free Detection of Explosives

EXP-SA：无受体爆炸物检测

• 批准号: 0731243
• 负责人: Vinayak Dravid
• 金额: $ 40万
• 依托单位: Northwestern University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-10-15 至 2011-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0731243&HistoricalAwards=false
• 关键词: EXP; SA; Receptor; Free; Detection

ABSTRACTObjective:The objective of this proposal is to develop a unique combination of multimodal detection scheme anchored by an innovative electronic signal transduction approach based on MOSFET-embedded microcantilevers coupled with in-situ MEMS heaters.Intellectual Merit: We propose to develop a receptor-free detection approach for chemical sensing and identifying explosives by exploiting their discriminating thermal response, in combination with an all-electronic MOSFET signal detection all of which are amenable to massively parallel and multiplexed mode for detection and with requisite orthogonality of sensor response to explosive vapors. Specifically, we plan to address the following intellectual challenges:1) Design and fabrication of MOSFET-embedded microcantilever sensors that can provide unprecedented sensitivity of nanomechanical detection of gases/vapors.2) Design and fabrication of MOSFET cantilevers that can be heated uniformly in a programmed manner within 50-100 milliseconds.3) Demonstration of thermal speciation of explosive components with high selectivity, to enable discrimination of relevant vapor species in explosives.4) Design of sample collection and fast preconcentrator units that can collect explosives within 10 seconds and regenerate the system within 10 seconds.5) Demonstration of detection of explosives and mixtures in the presence of interferents. Coupled with MOSFET-embedded microcantilevers for all-electronic signal transduction and detection approach, we believe that our combined approach provides for a unique and out-of-the-box initiative for highly selective detection of explosives.Broader Impact: The proposed sensor system theme will be incorporated in a sensor module as a part of Materials World Network (MWN) program at NU, which reaches thousands of high school students and hundreds of teachers, including DOD establishments. We will leverage other NU outreach programs under NCLT (teachers), NSEC (REUs) and MRC (MIN) to attract underrepresented students for research internship and graduate support. The proposed team will engage in local underrepresented student engineering societies. We will incorporate research themes in the ASME tutorial modules. Northwestern is involved in an ongoing collaboration with Dr. Barry Aprison team at the Chicago Museum of Science & Industry (CMSI) for a nanotechnology exhibit. Our team will help provide advice and input in the development of Nanotechnology exhibit at CMSI, including a theme on biochemical sensors. Collectively, we will help achieve effective integration of research with UG and graduate education, hands-on training, professional development and broader societal impact.

抽象目标：该提议的目的是建立一个由创新的电子信号转导方法锚定的多模式检测方案的独特组合全电动MOSFET信号检测所有这些都可以与大规模平行和多路复用模式进行检测，并具有传感器对爆炸性蒸气的必要正交性。具体而言，我们计划应对以下智力挑战：1）设计和制造由MOSFET嵌入的微型管理器传感器，可以提供空前的纳米力学检测灵敏度/蒸气的纳米力学检测灵敏度。2）设计和制造MOSFET悬臂在50-100毫米explive septions中均匀地均匀地置于50-100毫米套装中，选择性，为爆炸物中相关蒸气物种的歧视。4）样品收集和快速注解剂单元的设计，可以在10秒内收集爆炸物，并在10秒内重新生成系统。5）在存在干扰物的情况下证明爆炸物和混合物的检测。再加上用于全电动信号转导和检测方法的MOSFET包装的微型武器，我们认为我们的组合方法提供了一项独特而开箱即用的计划，以高度选择性地检测爆炸物的影响：拟议的传感器系统将在材料世界中的千分之一的nu nu nu nu nu nu nu nu nu semport of Sensor them semport in a never never of Sensor Sysem纳入。教师，包括国防部机构。我们将利用NCLT（教师），NSEC（REUS）和MRC（Min）的其他NU外展计划来吸引代表性不足的学生进行研究实习和研究生支持。拟议的团队将参与当地代表性不足的学生工程社会。我们将在ASME教程模块中纳入研究主题。 Northwestern与芝加哥科学与工业博物馆（CMSI）的Barry Aprison博士团队（CMSI）进行了纳米技术展览会的持续合作。我们的团队将帮助提供CMSI纳米技术展览开发的建议和投入，其中包括生化传感器的主题。总的来说，我们将帮助将研究与UG和研究生教育，动手培训，专业发展和更广泛的社会影响实现有效整合。