SGER: Observing the development of biofilm structure under controlled complex flow patterns

SGER：观察受控复杂流动模式下生物膜结构的发展

• 批准号: 0730976
• 负责人: Aaron Packman
• 金额: --
• 依托单位: Northwestern University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-11-15 至 2009-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0730976&HistoricalAwards=false
• 关键词: SGER; Observing; development; biofilm; structure

SGER ProposalCBET 0730976Aaron PackmanNorthwestern UniversityObserving the development of biofilm structure under controlled complex flow patterns The primary objective of this project is to develop and evaluate an innovative experimental system for in situ observation of the coupling of physical, chemical, and biological processes affecting the growth and structure of biofilms. The system will consist of a planar flow cell designed to provide well-controlled flow-induced heterogeneity in flow conditions while allowing direct in situ observation of physical/ chemical conditions by optical sensing techniques and microbial growth by microscopic methods. The system will allow the study of microbal communities of varying degrees of complexity. Current experimental systems for studying biofilms do not allow equal control and observation of all the factors that the proposed device will. Aside from developing a tool for research on biofilms, the project will evaluate the range of flow patterns that can be established and how they affect biofilm growth in the system. Biofilms are virtually ubiquitous in the natural environment and in many built systems, including water distribution systems, treatment plants, ship hulls, and concrete structures for waterways.

SGER PROPOLSCBET 0730976AARON PACKMANNORTHWESTERN UNIVESSIONS在受控的复杂流程模式下生物膜结构的发展开发该项目的主要目标是开发和评估一种创新的实验系统，以观察影响生长和结构生长的物理，化学，化学和生物学过程的原位观察。该系统将由一个平面流动池组成，旨在在流动条件下提供良好控制的流动诱导的异质性，同时通过光学传感技术和微生物生长通过微观方法直接观察物理/化学条件。该系统将允许研究各种复杂程度的微生物群落。当前用于研究生物膜的实验系统不允许平等控制和观察所提出的设备所将要的所有因素。除了开发生物膜研究工具外，该项目还将评估可以确定的流动模式范围以及它们如何影响系统中的生物膜生长。生物膜在自然环境中几乎无处不在，在许多建筑系统中，包括水分配系统，处理厂，船体和水道混凝土结构。