SBIR Phase I: Dynamic Web Application Development Environment for eLearning and Research

SBIR 第一阶段：用于电子学习和研究的动态 Web 应用程序开发环境

• 批准号: 0711715
• 负责人: Norah MacCuish
• 金额: $ 10万
• 依托单位: Mesa Analytics & Computing, LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0711715&HistoricalAwards=false
• 关键词: SBIR; Phase; Dynamic; Web; Application

This Small Business Innovation Research (SBIR) Phase I research project addresses the feasibility of designing a development framework that academics and industrial professionals can use to create dynamic Web applications for eLearning and research environments, as applied to broad areas of chemistry in drug discovery, but more specifically applied to synthetic organic chemistry in the area of drug design. The use of computer driven learning and research in the broader field of chemistry is becoming more commonplace, yet there is still a considerable gap between academic pedagogy and the use of computers in industrial methods and workflows at the juncture of synthetic organic chemistry and drug discovery. Presently, there are very few software tools, at the disposal of synthetic organic chemists, that are easy to use and well integrated for the use in either eLearning or research that reflect the industrial experience of those working in the field of drug discovery. Academics and industrial professionals in the computer chemistry area of drug discovery often cobble together disparate software packages from freeware in the case of the former, and from commercial sources in the case of the latter for instruction, on the job training, or research purposes. Dynamic web application environments provide an extremely effective way to deliver the integration of such software, while making the interaction of the many underlying programs invisible to the user. Having a way to modify and otherwise extend such environments, and thereby tailor them to very specific eLearning (e.g. distant learning, industrial training), industrial workflows, or research needs, provides enormous flexibility and power. This project is at the very leading edge of what in the industry is known as 'Chemist of the Future' projects, whereby even synthetic chemists will train and perform research via computer. The worldwide market for such a tool extends across thousands of academic institutions -- rural, small colleges to major universities, to synthetic organic chemistry programs in industrial laboratories. The proposed development framework is broad enough fro ti to be used in related scientific disciplines and industries.

这项小型企业创新研究（SBIR）I阶段研究项目探讨了设计一个开发框架的可行性，该框架可以使用该框架来创建用于电子学习和研究环境的动态Web应用程序，该应用程序应用于药物发现中的广泛领域，但更专门应用于药物设计领域的合成有机化学领域。在更广泛的化学领域中，使用计算机驱动的学习和研究变得越来越普遍，但是在合成有机化学和药物发现的关键时期，学术教学法与计算机在工业方法和工作流程中的使用仍然存在很大差距。目前，很少有软件工具可以使用合成有机化学家，这些工具易于使用，并且可以很好地整合在电子学习或研究中，这反映了在药物发现领域工作的人的工业经验。药物发现的计算机化学领域的学术界和工业专业人员通常会在前者的情况下将自由软件的不同软件包拼凑在一起，而在后者的情况下，从商业来源进行了教学，就业培训或研究目的。动态Web应用程序环境提供了一种非常有效的方法来交付此类软件的集成，同时使用户看不见许多基础程序的互动。有一种方法可以修改和以其他方式扩展此类环境，从而将它们定制为非常特定的电子学习（例如遥远的学习，工业培训），工业工作流程或研究需求，可提供巨大的灵活性和力量。该项目处于行业中被称为“未来化学家”项目的前沿，即使合成化学家也将通过计算机训练和进行研究。这种工具的全球市场跨越了成千上万的学术机构 - 农村，小型大学到大型大学，到工业实验室的合成有机化学计划。提出的发展框架足够广泛，可以用于相关的科学学科和行业。