CAREER: Virtual Functional Anatomy

职业：虚拟功能解剖学

• 批准号: 0507854
• 负责人: Frances Sheehan
• 金额: --
• 依托单位: University of Maryland at Baltimore
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0507854&HistoricalAwards=false
• 关键词: CAREER; Virtual; Functional; Anatomy

0134205SheehanUnder this CAREER Award, the musculoskeletal system at the component level (joint anatomy and tissue dynamics) during functional movements will be characterized. Characterization will be accomplished by developing a set of interdisciplinary tools (virtual functional anatomy - VFA) that will allow the accurate and precise measurement of 3D static and dynamic musculoskeletal anatomy. Fast-PC MRI (phase contrast magnetic resonance imaging) will be be combined with high-resolution 3D musculoskeletal models to create subject-specific 3D total joint anatomy models, animated based on actual joint movements during volitional movement. The initial focus will be on the musculoskeletal kinematics and kinetics of the knee joint while subjects extend and flex their knees. Stress-strain properties of the patellar and quadriceps tendons along with their moment arms, strain within the anterior and posterior cruciate ligaments and the contribution of each quadriceps muscle to the resultant extensor force will be determined. Once developed, the modular VFA tool can be adapted to other musculoskeletal systems utilizing other sources of dynamic and/or imaging data. The educational component focuses on developing a mechanical engineering Master's level curriculum specializing in biomechanics, which would be based on two research-oriented courses-Imaging Technologies and Functional Movement Analysis--that would integrate the VFA produced through the research and be enhanced with web-based experimental programs. Outreach programs designed to allow young women the opportunity to explore potential careers in science or engineering will continue to be supported.

0134205SHEEHANUNDE这个职业奖，功能运动过程中组件水平的肌肉骨骼系统（关节解剖学和组织动力学）将被表征。 将通过开发一组跨学科工具（虚拟功能解剖 - VFA）来实现表征，该工具将允许对3D静态和动态肌肉骨骼解剖结构进行准确而精确的测量。 快速PC MRI（相位对比度磁共振成像）将与高分辨率的3D肌肉骨骼模型结合使用，以创建受试者特异性的3D总关节解剖模型，该模型根据自愿运动期间的实际关节运动而动画。 最初的重点将放在膝关节的肌肉骨骼运动学和动力学上，而受试者延伸并弯曲膝盖。 tellar和股四头肌肌腱的应力应变特性以及它们的矩臂，在前交叉和后交叉韧带内的应变，以及每个股四头肌肌肉对产生的伸肌的贡献。 开发后，可以利用其他动态和/或成像数据来源的模块化VFA工具适应其他肌肉骨骼系统。 该教育组成部分着重于开发专门研究生物力学的机械工程硕士水平课程，该课程将基于两种面向研究的课程 - 模仿技术和功能运动分析 - 这将整合通过研究生产的VFA，并可以增强基于Web的实验计划。 旨在使年轻妇女有机会探索科学或工程领域的潜在职业的外展计划将继续得到支持。