Biomimetic Smart Materials and Sensors

仿生智能材料和传感器

• 批准号: 0437236
• 负责人: Amy Shen
• 金额: $ 10万
• 依托单位: Washington University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-15 至 2006-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0437236&HistoricalAwards=false
• 关键词: Biomimetic; Smart; Materials; Sensors

Biomimetic smart materials and sensorsAmy ShenWith the discovery of the plant protein forisome (Knoblauch et al. 2003), a novel nastic non-living, ATP-independent biological material became available to the designer of smart materials for advanced actuating and sensing. The in vitro studies of Knoblauch et al. show that forisomes (1-3 micron wide and 10-30 micron long) can be repeatedly stimulated to contract and expand anisotropically by the application of a pH and calcium concentration shift. Due to their unique features, forisomes have the potential to outperform current smart materials such as ATP-dependent actuators and synthetic hydrogels/polymers as advanced multi-functional smart sensors, valves, and actuators as biomimetic devices. The central goal of this project is to engineer biomimetic smart materials based on ATP-independent plant protein forisomes that will outperform conventional actuators. With many unknowns and challenges, the proposed research is highly exploratory and we will attack these issues using a combination of experiment, modeling, and numerical simulation. The high reward associated with this project comes from establishing the possibility of synthesizing a biomimetic composite with all-in-one, multi-functional (actuation, sensing) component within microdevices and morphing structures. This work will be a major advancement over existing technologies (using, for example, hydrogels, PZT, shape memory alloy) for actuation and sensing in one-piece. Forisome based biomimetic smart materials are important in civil and mechanical applications such as aircraft and small scale vehicle morphing, mechanical adaptive systems, structural noise and vibration control, and will lead to many potential applications in environmental monitoring, drug delivery, biomedical and defense applications.Broader Impact: Research and EducationThe proposed project promises to have a wide-ranging impact not only on fundamental knowledge concerning the synthesis of a new generation biomimetic smart materials for advanced actuating and sensing, but also on the area of other emerging nano-, bio-, and micro-technologies.Each year, PI Amy Shen has set aside two undergraduate research positions in her laboratory to members of Society of Women Engineering at Washington University. Mechanical Engineering junior Elizabeth Henderson has been fabricating microfluidic devices and learning AFM procedure to perform materials characterizations during Spring 2004 and will continue her research on this project starting Fall, 2004. This experience will provide students with the opportunity to learn how to work on a well-defined research project with multidisciplinary interactions in novel materials, fluid mechanics, plant biology, heat transfer, and process design.

仿生智能材料和传感器Amy Shen 随着植物蛋白 forisome 的发现（Knoblauch 等人，2003 年），一种新颖的非生命、不依赖 ATP 的生物材料可供智能材料设计者用于高级驱动和传感。 Knoblauch 等人的体外研究。研究表明，通过施加 pH 值和钙浓度变化，可以反复刺激体（1-3 微米宽，10-30 微米长）各向异性收缩和膨胀。由于其独特的功能，forisomes 有可能超越当前的智能材料，例如 ATP 依赖性执行器和合成水凝胶/聚合物，作为先进的多功能智能传感器、阀门和执行器作为仿生设备。该项目的中心目标是设计基于不依赖于 ATP 的植物蛋白异构体的仿生智能材料，其性能将优于传统的执行器。 由于存在许多未知因素和挑战，所提出的研究具有高度探索性，我们将结合实验、建模和数值模拟来解决这些问题。与该项目相关的高回报来自于建立了在微设备和变形结构中合成具有一体式多功能（驱动、传感）组件的仿生复合材料的可能性。这项工作将是对现有一体式驱动和传感技术（例如使用水凝胶、PZT、形状记忆合金）的重大进步。基于Forisome的仿生智能材料在民用和机械应用中非常重要，例如飞机和小型车辆变形、机械自适应系统、结构噪声和振动控制，并将在环境监测、药物输送、生物医学和国防应用中带来许多潜在应用。更广泛的影响：研究和教育拟议的项目不仅对合成用于先进驱动和传感的新一代仿生智能材料的基础知识产生广泛的影响，而且对其他新兴纳米、每年，PI Amy Shen 都会在她的实验室中为华盛顿大学女性工程学会的成员预留两个本科生研究职位。机械工程大三学生 Elizabeth Henderson 在 2004 年春季期间一直在制造微流体装置并学习 AFM 程序来执行材料表征，并将从 2004 年秋季开始继续她对该项目的研究。这种经验将为学生提供学习如何在井上工作的机会。 -在新型材料、流体力学、植物生物学、传热和工艺设计方面具有多学科相互作用的明确研究项目。