Acquisition of NMR Spectrometer for Chemistry

购置化学用核磁共振波谱仪

• 批准号: 0412901
• 负责人: Claude Yoder
• 金额: $ 52.73万
• 依托单位: Franklin and Marshall College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2007-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0412901&HistoricalAwards=false
• 关键词: Acquisition; NMR; Spectrometer; Chemistry

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Franklin and Marshall College will acquire a 400 MHz nuclear magnetic resonance (NMR) Spectrometer. This equipment will enable researchers to carry out studies on atranyl-nucleosides as transition state analogs in the study of the hammerhead ribozyme, in vivo incorporation of photocrosslinked amino acids to increase protein stability, molecular recognition using fluorescent chemsensors, the mechanism of the [1,3]carbon shift, hypercoordination in organogermanium compounds, and the structure-lattice energy relationship in lead double salts. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organometallic chemistry and biochemistry.

通过主要研究工具（MRI）计划的奖项，富兰克林和马歇尔学院的化学系将获得400 MHz核磁共振（NMR）光谱仪。该设备将使研究人员能够在锤头核酶研究中对苯基核苷作为过渡态类似物进行研究，在体内掺入光叠型链接氨基酸，以增加蛋白质稳定性，以增加蛋白质稳定性，使用荧光化学体的分子识别（3]碳构成，较高的碳元素，较高量和含量的含量。盐。 核磁共振（NMR）光谱是化学家可用于阐明分子结构的最强大工具之一。它用于识别未知物质，以表征分子中原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行边境研究的化学家来说，获得最先进的NMR光谱仪至关重要。这些NMR研究的结果将对合成有机金属化学和生物化学产生影响。