AToL: Collaborative Research: AmphibiaTree---An Integrated Phylogenetic and Bioinformatics Approach to the Tree of Amphibians

AToL：合作研究：AmphibiaTree——两栖动物树的综合系统发育和生物信息学方法

• 批准号: 0334939
• 负责人: David Wake
• 金额: $ 101.8万
• 依托单位: University of California-Berkeley
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0334939&HistoricalAwards=false
• 关键词: AToL; Collaborative; Research; AmphibiaTree; Integrated

0334939Wake and Wake A grant has been awarded to Drs. David Wake and Marvalee Wake at the University of California at Berkeley, as part of a four-institution collaboration, to study phylogenetic relationships of the living amphibians and their close fossil relatives. Living Amphibians are a prominent part of the Earth's vertebrate fauna and include three orders: the caecilians (Gymnophiona), salamanders (Caudata), and frogs and toads (Anura). Despite recent advances in discovering and describing their diversity, many critical questions in amphibian evolution remain unresolved and a fresh analysis of evolutionary relationships is needed to take new discoveries into account. Furthermore, the recent decline and apparent extinction of amphibians from many environments makes it urgent that we discover and classify the diversity present today. A team of seven investigators from diverse institutions (University of Texas at Austin, University of California at Berkeley, Harvard University, and the University of Kansas) and their colleagues will collaborate to resolve modern amphibian relationships. Field sampling in biodiversity hotspots will provide materials of new or previously unsampled lineages. Anatomical and morphological data from living and fossil forms will be combined with DNA sequences from a set of defined mitochondrial and nuclear genes for as many species as possible, and will be integrated with existing data sets. Analysis of these large data sets will be used to gain insight into such questions as repeated patterns of evolution, geographic patterns, and rates of evolution. Drs. Wake and Wake and their students and colleagues will focus on molecular and morphological studies of caecilians and salamanders, with targeted field work in South America and Africa, and will have special responsibility for the AmphibiaWeb component, as well as contributing to the overall integration of molecular and morphological datasets for phylogenetic analysis. Understanding the evolutionary history of modern amphibians is critical for developing conservation strategies for amphibians as well as completing the vertebrate portion of the tree of life. The project will involve extensive student training and interaction with US and international colleagues. Communication with the public will utilize web resources, especially AmphibiaWeb, an existing site that will be expanded and further developed to provide information on all species of amphibians for professionals and the public at large. AmphibiaWeb will also provide training opportunities for students and senior professionals to enable them more effectively to communicate their findings.

0334939 Wake and Wake已向Drs授予了一笔赠款。作为四机构合作的一部分，戴维·韦克（David Wake）和马瓦利（Marvalee）在加利福尼亚大学伯克利分校（University of Berkeley）唤醒，以研究活着的两栖动物及其亲密化石亲戚的系统发育关系。活着的两栖动物是地球脊椎动物动物动物区系的重要组成部分，包括三个命令：盲肠（体操运动物），sal（caudata），青蛙和蟾蜍（Anura）。尽管最近发现和描述了它们的多样性，但两栖动物进化中的许多关键问题仍未解决，并且需要对进化关系进行新的分析以考虑新发现。 此外，在许多环境中，两栖动物最近的下降和明显的灭绝使我们迫切发现并分类当前的多样性。 由来自不同机构的七名调查人员组成的团队（得克萨斯大学奥斯汀分校，加利福尼亚大学伯克利分校，哈佛大学和堪萨斯大学）及其同事将合作解决现代两栖动物的关系。 生物多样性热点中的现场采样将提供新的或以前未采样的谱系的材料。来自生活和化石形式的解剖学和形态数据将与尽可能多的物种的一组定义的线粒体和核基因的DNA序列结合使用，并将与现有数据集集成。 对这些大数据集的分析将用于洞悉诸如反复演变，地理模式和进化速率等问题。博士。 Wake and Wake以及他们的学生和同事将着重于对Caecilians和Salamanders的分子和形态学研究，在南美和非洲具有针对性的现场工作，并将对两栖动物Web组件负有特殊责任，并为分子和形态数据集的整体整合做出系统发育分析。了解现代两栖动物的进化史对于为两栖动物制定保护策略以及完成生命之树的脊椎动物部分至关重要。 该项目将涉及与美国和国际同事的广泛培训和互动。 与公众的沟通将利用Web资源，尤其是AmphibiaWeb，这是一个现有网站，将被扩展并进一步开发，以提供有关专业人士和整个公众的所有两栖动物的信息。 AmphibiaWeb还将为学生和高级专业人员提供培训机会，以使他们更有效地传达他们的发现。