SBIR Phase I: Low Cost, Needleless Drug Injection System

SBIR 第一阶段：低成本、无针药物注射系统

• 批准号: 0319295
• 负责人: James Scherer
• 金额: $ 10万
• 依托单位: NOVAWAVE TECHNOLOGIES
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2004-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0319295&HistoricalAwards=false
• 关键词: SBIR; Phase; Low; Cost; Needleless

This Small Business Innovation Research (SBIR) Phase I project will demonstrate the feasibility of producing a novel, needleless drug injection system for widespread vaccination applications. The key element in the technology will be a novel high pressure pumping device. This device will enable high pressure flows to be precisely and easily controlled by the user in order to control injection drug amount. This is a capability currently lacking in existing low cost needleless injector technology. The Phase I project will show that the high pressure pumping device actually works. The follow on Phase II effort will focus on building a prototype system that will integrate the pump with the control electronics and injection nozzle for subsequent testing. The commercial application of this project is in the area of drug delivery. The proposed needleless injection device is expected to be reused thousands of times with a single low voltage battery source and will be invaluable for widespread vaccination use in the field for domestic as well as foreign markets. The unique ability to precisely meter injection volume will enable the device to be easily adjusted in the field to deliver a dosage appropriate for the associated weight, age, or physical condition of the patient.

这项小型企业创新研究（SBIR）第一阶段项目将证明生产一种新颖的，无用的药物注入系统用于广泛疫苗接种应用的可行性。该技术的关键要素将是一种新型的高压抽水装置。该设备将使用户精确，易于控制高压流，以控制注射药物量。这是目前缺乏现有低成本无针喷射器技术的功能。第一阶段项目将表明高压抽水设备实际上有效。 II阶段工作的后续工作将集中在建立一个原型系统上，该系统将将泵与控制电子和注入喷嘴集成在一起，以进行后续测试。该项目的商业应用在药物输送领域。拟议的无针注射装置预计将使用单个低压电池源重复使用数千次，对于在国内和国外市场的广泛疫苗接种而言，将是无价的。精确仪表注入体积的独特能力将使设备在现场轻松调整，以提供适合患者相关的体重，年龄或身体状况的剂量。