New Components of the Ethylene Signaling and Response Pathway

乙烯信号和响应途径的新成分

• 批准号: 0315992
• 负责人: Jose Alonso
• 金额: $ 20万
• 依托单位: North Carolina State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0315992&HistoricalAwards=false
• 关键词: New; Components; Ethylene; Signaling; Response

The plant hormones ethylene and auxin are key regulators of many physiological processes, including plant growth, fruit ripening, defense against pathogens, and aging. This research is directed at understanding the mechanisms of action of ethylene and its interactions with auxin. Such knowledge is crucial to the ability to manipulate plant responses to the environment for the purpose of improving agricultural production, forestry and horticulture. In this project, genetic and molecular tools will be employed to clone three novel mutants that possess reduced sensitivity to ethylene, as well as to dissect the role of the corresponding genes in the interaction between ethylene and auxin. Preliminary data imply the involvement of the new ethylene genes in the regulation of the biosynthesis of auxin precursors. These studies are expected to shed light on the cross-talk between the two hormones.The education and training components will be an integral part of this project. Graduate, undergraduate and high-school students will have the opportunity to directly participate in this scientific effort and get "hands-on" research experience in the exciting field of molecular genetics in the plant model organism Arabidopsis thaliana. This project will allow Dr. Alonso to continue with his ongoing participation in several graduate and undergraduate training programs. The programs will serve to attract and encourage students from ethnic minorities, especially Hispanics, to become interested in science and to further pursue their aspirations for higher education and experimental research.

植物激素乙烯和生长素是许多生理过程的关键调节剂，包括植物生长，水果成熟，防御病原体和衰老。这项研究旨在理解乙烯及其与生长素相互作用的作用机理。这种知识对于为了改善农业生产，林业和园艺而操纵植物对环境的反应的能力至关重要。 在这个项目中，将使用遗传和分子工具来克隆三个具有降低乙烯敏感性的新型突变体，并剖析相应基因在乙烯和生长素之间相互作用中的作用。 初步数据意味着新乙烯基因参与生长素前体的生物合成调节。 这些研究有望阐明两种激素之间的串扰。教育和培训组成部分将是该项目不可或缺的一部分。 研究生，本科和高中生将有机会直接参加这项科学工作，并在植物模型有机体拟南芥中令人兴奋的分子遗传学领域获得“动手”研究经验。该项目将使Alonso博士能够继续参加多个研究生和本科培训计划。这些计划将吸引和鼓励来自少数民族，尤其是西班牙裔的学生对科学产生兴趣，并进一步追求他们对高等教育和实验研究的愿望。