Brassinosteroid-Auxin Synergism to Dissect Hormone Response Pathways in Arabidopsis

油菜素类固醇-生长素协同作用剖析拟南芥激素反应途径

• 批准号: 0315845
• 负责人: Joanne Chory
• 金额: $ 57.5万
• 依托单位: The Salk Institute for Biological Studies
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2007-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0315845&HistoricalAwards=false
• 关键词: Brassinosteroid; Auxin; Synergism; Dissect; Hormone; Brassinosteroid; Auxin; Synergism; Dissect; Hormone

Plants are exquisitely sensitive to their light environment. Recent studies in the P.I.'s laboratory indicate that the plant hormones auxin and brassinosteroids (BRs) act in close proximity to modulate the seedling light response. The auxin and BR pathways have been studied individually in some detail, but significant gaps in each pathway exist. This project aims to identify components that may be shared between the auxin and BR signaling pathways. The primary aims are: (1) to characterize the BR-auxin interaction in Arabidopsis using existing physiological and genetic tools and (2) to uncover novel signal transduction components utilized by both hormones. This research will address the impact of the interaction between these hormones in regulating such diverse responses as changes in gene expression, cell expansion and division, and vascular differentiation. The long-term objective is to completely understand the signaling networks that regulate seedling development, and to relate this to general mechanisms of signal transduction in other organisms.

植物对它们的轻度环境非常敏感。 P.I.实验室的最新研究表明，植物激素生长素和腕足激素（BRS）的作用紧靠，以调节幼苗的光反应。生长素和BR途径已详细研究，但存在每个途径的显着差距。 该项目旨在确定生长素和BR信号通路之间可能共享的组件。主要目的是：（1）使用现有的生理和遗传工具以及（2）发现两种激素使用的新型信号转导组件来表征拟南芥中的BR-乳酸相互作用。这项研究将解决这些激素之间的相互作用在调节基因表达，细胞扩张和分裂以及血管分化等多种反应中的相互作用。 长期目标是完全了解调节幼苗发育的信号网络，并将其与其他生物体信号转导的一般机制联系起来。