GOALI: MEMS Based Sensors and Actuators for Medical and Biological Applications

GOALI：用于医疗和生物应用的基于 MEMS 的传感器和执行器

• 批准号: 0201773
• 负责人: Frank Lewis
• 金额: $ 23.51万
• 依托单位: University of Texas at Arlington
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-10-01 至 2006-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0201773&HistoricalAwards=false
• 关键词: GOALI; MEMS; Based; Sensors; Actuators

0201773LewisMechanical ventilators play critical roles in saving lives of patients with pulmonary dysfunction. Emergency manual resuscitators are used daily by paramedics to revive trauma patients. For life support these devices must sense respiratory pressures. Size and electric power requirements of current pressure transducers restrict sensing of pressures to points within the machine and distal to patient airways. This can severely degrade the efficacy of the ventilator or even create patient trauma, as the natural airway anatomical variability creates unpredictable pressure losses. Moreover, chronic pulmonary illnesses due to air pollution and asthma are increasing. To understand and quantify the effects on respiration, better sensors are needed.This GOALI proposal focuses on designing, fabricating and testing in vivo novel microelectromechanical systems (MEMS) pressure and flow sensors based purely on optics that can be deployed into the airways, e.g. into endotracheal tubes, nasal masks, ventilators and resuscitators. The research team, which includes collaborations between three academic units and three industrial partners, will perform fundamental research in detecting sensor activation effects using purely optical techniques and will develop new design, analysis, testing, calibration, and production practices for optical MEMS biosensors. New digital signal processing approaches will be developed to obtain required accuracies and ranges of measurement. .As part of the outreach plan, the GOALI team will 1) develop a new design course on MEMS sensor and actuator analysis, design, prototyping, and applications, including biomedical, 2) develop courseware that can be used over the internet for training of industry engineers and students and 3) offer two industrial seminars on-site at industrial partners.

0201773 Lewismanical呼吸机在挽救肺部功能障碍患者的生命中起着至关重要的作用。护理人员每天使用紧急手动复苏者来复兴创伤患者。为了生命，这些设备必须感觉到呼吸压力。当前压力传感器的尺寸和电力需求将压力的传感限制在机器内部的点和远端的距离。这会严重降解呼吸机的功效，甚至会造成患者创伤，因为天然气道解剖变异性会造成不可预测的压力损失。此外，由于空气污染和哮喘引起的慢性肺疾病正在增加。为了理解和量化对呼吸的影响，需要更好的传感器。此目标建议着重于在体内设计，制造和测试新型微电动机电系统（MEMS）压力和流动传感器，纯粹基于可以部署到气道中的光学器件，例如进入气管管，鼻口罩，呼吸机和复苏器。 该研究团队包括三个学术单位和三个工业伙伴之间的合作，将使用纯粹的光学技术来检测传感器激活效果，并将为光学MEMS生物传感器开发新的设计，分析，测试，校准和生产实践。 将开发新的数字信号处理方法，以获得所需的精度和测量范围。 作为外展计划的一部分，目标团队将1）开发有关MEMS传感器和执行器分析，设计，原型和应用程序的新设计课程，包括生物医学，2）开发可以通过Internet使用的课程来培训行业工程师和学生以及3）在工业合作伙伴的现场提供两个工业研讨会。