Postdoctoral Research Fellowship in Biological Informatics for FY2001

2001财年生物信息学博士后研究奖学金

• 批准号: 0107581
• 负责人: Daniel Butts
• 金额: $ 10万
• 依托单位: Butts, Daniel A
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0107581&HistoricalAwards=false
• 关键词: Postdoctoral; Research; Fellowship; Biological; Informatics

This action funds an NSF Postdoctoral Research Fellowship in Biological Informatics for FY2001. The fellowship supports research and training at the postdoctoral level at the intersection of biology and the informational, computational, mathematical, and statistical sciences. The goal of the fellowship is to provide training to a young scientist in preparation for a career in biological informatics in which research and education will be integrated. There is an increasing need for training in biological informatics at all occupational levels, and it is expected that Fellows trained through these fellowships will play important roles in training of the future workforce.The research and training plan for this fellowship is entitled "How does neural activity instruct the system-wide modifications in brain structure that occur during development of the visual system?" Spontaneously generated "retinal waves" are required for early visual system development. This research uses a combined theoretical and experimental approach to determine (1) how physiologically relevant neural input causes appropriate modifications at individual retinogeniculate synapses, and (2) how these retinal-wave-driven modifications result in system-wide competition that drives retinogeniculate development.

这项行动资助了 2001 财年 NSF 生物信息学博士后研究奖学金。 该奖学金支持生物学与信息、计算、数学和统计科学交叉领域的博士后水平的研究和培训。该奖学金的目标是为年轻科学家提供培训，为将研究和教育融为一体的生物信息学职业做好准备。所有职业级别对生物信息学培训的需求日益增长，预计通过这些奖学金培训的研究员将在未来劳动力的培训中发挥重要作用。该奖学金的研究和培训计划的标题是“神经网络如何活动指导视觉系统发育过程中发生的大脑结构的全系统改变？” 早期视觉系统发育需要自发产生的“视网膜波”。 这项研究采用理论和实验相结合的方法来确定（1）生理相关的神经输入如何引起单个视网膜突触的适当修饰，以及（2）这些视网膜波驱动的修饰如何导致全系统竞争，从而驱动视网膜神经发育。