Absolute Kinetic Studies of Carbene Fragmentation and Related Reactions

卡宾裂解及相关反应的绝对动力学研究

• 批准号: 0091368
• 负责人: Robert Moss
• 金额: $ 44.5万
• 依托单位: Rutgers University New Brunswick
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-01-01 至 2004-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0091368&HistoricalAwards=false
• 关键词: Absolute; Kinetic; Studies; Carbene; Fragmentation

With this renewal award the Organic and Macromolecular Chemistry Program continues its support for the work of Dr. Robert A. Moss of the Department of Chemistry at Rutgers University New Brunswick campus in New Jersey. The research involves fundamental studies of carbenes and related reactive intermediates generated by laser flash photolysis, and followed by UV and IR absorption. Of particular interest is the study of the fragmentation reactions of alkoxyhalocarbenes (ROCX), where the rates and pathways are expected to depend on the natures of the R group and the halogen X. Quantum mechanical tunneling in intramolecular rearrangements will be studied using the cyclopropylmethyl carbenes C3H5CH2CCl and C3H5CD2CCl. High level computational studies carried out in collaboration with theoreticians will accompany the experimental work.This ongoing research involves fundamental studies of carbenes - short-lived and reactive intermediates with only two groups attached to carbon rather than the usual four - which can be generated in solution by very short laser flashes. The concentrations of the intermediates can then be followed by their absorption of ultraviolet or infrared light. This is classical physical organic chemistry, and is expected to provide excellent training for the students and colleagues involved, through the rigorous scientific approach used and the variety of strategies and techniques involved.

有了这一续签奖，有机和大分子化学计划将继续对新泽西州新泽西州新不伦瑞克校区化学系的Robert A. Moss博士的工作支持。 该研究涉及对激光闪光照射产生的碳烯和相关反应性中间体的基本研究，然后进行紫外线和IR吸收。 特别令人感兴趣的是研究烷氧基甲苯（ROCX）的碎片反应，其中预计速率和途径依赖于R组的本质和卤素X的本性。 C3H5CH2CCL和C3H5CD2CCL。 与理论家合作进行的高级计算研究将伴随实验性工作。这项正在进行的研究涉及对卡贝尼斯的基本研究 - 短寿命和反应性中间体，只有两组附在碳而不是通常的四组 - 可以在解决方案中生成的四组 - 在很短的激光闪烁时。 然后，中间体的浓度可以随后吸收紫外线或红外光。 这是经典的物理有机化学，预计将通过严格的科学方法以及所涉及的各种策略和技术为所涉学生和同事提供出色的培训。