2000 Gordon Research Conference on the Biology of Spirochetes

2000 年戈登螺旋体生物学研究会议

• 批准号: 0070863
• 负责人: Steven Norris
• 金额: $ 0.5万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-02-01 至 2001-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0070863&HistoricalAwards=false
• 关键词: 2000; Gordon; Research; Conference; Biology

The fourth Gordon Research Conference on the Biology of Spirochetes is the only ongoing international meeting devoted to basic research on spirochetes, which comprise a separate phylum of the Bacteria. These organisms have a unique but common structure and mode of motility. There are free-living spirochetes, whereas others are parasitic for arthropod hosts including termites. Several other species cause disease in humans and animals. Recently, termite gut spirochetes have for the first time been cultured and were found to augment degradation of polymers such as cellulose. As a group, these organisms are difficult to study because of the lack of a system for continuous in vitro culture (in some cases) and adequate genetic systems. However, the recent publication of the genomic sequences for two spirochete species provide a wealth of information that is now being incorporated into studies on the biology of these bacteria. Furthermore, significant progress has recently been made in developing genetic exchange systems that should be applicable to both free living and pathogenic spirochetes. Additionally, the new developments of devising methods to cultivate termite gut spirochetes has broad application, as this basic knowledge is now being translated into cultivating spirochetes associated certain human diseases. The first three Biology of Spirochetes Gordon Conferences were well-received. For the 2000 conference, 150 faculty, graduate students, postdoctoral fellows, and industrial scientists are anticipated. Special attention will be made to obtain adequate representation of young investigators. The planned oral presentations and poster sessions will provide a forum for discussion and exchange of ideas. The past conferences have led to important collaborations between laboratories.

第四届戈登螺旋体生物学研究会议是唯一一项致力于螺旋体基础研究的国际会议，该会议包括细菌的单独门。这些生物具有独特但常见的结构和运动方式。有自由生活的螺旋体，而其他螺旋体是包括白蚁在内的节肢动物宿主的寄生虫。其他几种物种在人类和动物中引起疾病​​。最近，白蚁肠螺旋体首次被培养，并被发现增加聚合物（例如纤维素）的降解。作为一个小组，由于缺乏连续体外培养的系统（在某些情况下）和适当的遗传系统，因此这些生物很难研究。但是，最近出版了两个螺旋体物种的基因组序列提供了大量信息，这些信息现在已纳入有关这些细菌生物学的研究中。此外，最近在开发应适用于自由生活和致病性螺旋体的遗传交换系统方面取得了重大进展。此外，设计方法来培养白蚁肠螺旋体的新发展具有广泛的应用，因为现在将这种基本知识转化为与某些人类疾病相关的螺旋体。螺旋体戈登会议的前三个生物学受到了良好的欢迎。 在2000年的会议上，预计有150名教职员工，研究生，博士后研究员和工业科学家。将特别注意以获得年轻研究人员的足够代表。计划的口头演讲和海报会议将为讨论和交流思想提供论坛。过去的会议导致实验室之间的重要合作。