Postdoctoral Research Fellowship in Biological Informatics for FY-1999

1999财年生物信息学博士后研究奖学金

• 批准号: 9974207
• 负责人: Dean Adams
• 金额: $ 10万
• 依托单位: Fellowships
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-01 至 2001-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9974207&HistoricalAwards=false
• 关键词: Postdoctoral; Research; Fellowship; Biological; Informatics

This action funds an NSF Postdoctoral Research Fellowship in Biological Informatics for 1999.The research and training plan is in the area of biophysics and is entitled "Comparison of three-dimensional protein structures using geometric morphometric methods: an assessment of structural similarity." Geometric morphometric algorithms are being used to identify proteins with similar three-dimensional structures. These methods compare proteins using the x,y,z coordinates of homologous points and are robust to heterogeneous variation among landmarks. They compare multiple protein structures simultaneously and can thus be used to construct a protein structure space for identifying functionally similar proteins.

该行动资助了 1999 年 NSF 生物信息学博士后研究奖学金。该研究和培训计划属于生物物理学领域，题为“使用几何形态测量方法比较三维蛋白质结构：结构相似性评估”。 几何形态测量算法被用来识别具有相似三维结构的蛋白质。 这些方法使用同源点的 x、y、z 坐标来比较蛋白质，并且对于地标之间的异质变化具有鲁棒性。 它们同时比较多个蛋白质结构，因此可用于构建蛋白质结构空间以识别功能相似的蛋白质。