Dissertation Research: Molecular Phylogenetics of Neotropical Oryzomyine Rodents (Muridae: Sigmondontinae)

论文研究：新热带稻鼠类（鼠科：Sigmondontinae）的分子系统发育

• 批准号: 9801056
• 负责人: James Patton
• 金额: $ 1万
• 依托单位: University of California-Berkeley
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-06-15 至 2000-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9801056&HistoricalAwards=false
• 关键词: Dissertation; Research; Molecular; Phylogenetics; Neotropical

9801056 PATTON Rats and mice of the subfamily Sigmodontinae comprise the largest group of living mammals in South America, with some 250 species occupying all habitats throughout the continent. One of the subgroups of this diverse assemblage is the Oryzomyini, a group ("tribe") of about 15 genera and 100 species that occur from the grasslands of the high Andes to the Amazon rainforest. Many of these have highly localized ranges and are of conservation concern; others are widespread and have been implicated as vectors in human diseases. Little is certain about the historical (phylogenetic) relationships among rodents in this tribe; it is thought that they are descended from North American migrants. Resolving these relationships is a complex problem that presents a significant scientific challenge. A robust reconstruction would provide a historical framework for informed management decisions for those species of conservation concern (such as those endemic to the Galapagos Islands) as well as for those implicated as vectors in major human diseases (such as hanta virus). In this doctoral dissertation research, James L. Patton and student Luis F. Garcia will reconstruct the phylogeny of the Oryzomyini, principally by comparing DNA sequences from several genes in the mitochondrion and nucleus. The "combined gene" approach should provide high resolution of the phylogeny at all taxonomic levels within the tribe. The phylogeny should allow the researchers to test some prevailing ideas about when and where these rodents first became established in South America, and how they diversified after their introduction.

9801056 PATTON Sigmodontinae 亚科的大鼠和小鼠是南美洲最大的现存哺乳动物群体，约有 250 个物种占据了整个大陆的所有栖息地。 Oryzomyini 是这一多样化组合的亚群之一，该群（“部落”）约有 15 个属和 100 个物种，分布在安第斯山脉高地的草原到亚马逊雨林。 其中许多具有高度局部化的范围并受到保护关注；其他病毒则广泛存在，并被认为是人类疾病的媒介。 关于这个部落中啮齿类动物之间的历史（系统发育）关系还不清楚；人们认为他们是北美移民的后裔。 解决这些关系是一个复杂的问题，提出了重大的科学挑战。 强有力的重建将为那些受保护的物种（例如加拉帕戈斯群岛特有的物种）以及作为主要人类疾病媒介的物种（例如汉塔病毒）的知情管理决策提供一个历史框架。 在这篇博士论文研究中，James L. Patton 和学生 Luis F. Garcia 将主要通过比较线粒体和细胞核中多个基因的 DNA 序列来重建 Oryzomyini 的系统发育。 “组合基因”方法应该提供部落内所有分类水平的系统发育的高分辨率。 系统发育应该允许研究人员测试一些关于这些啮齿动物首次在南美洲定居的时间和地点，以及它们在引入后如何多样化的流行观点。